Effects of Perineural Capsaicin Treatment on Compound Action Potentials of Superior Laryngeal Nerve Afferents in Sevoflurane-Anesthetized Dogs.
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概要
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Effects of perineural capsaicin (CAPS) treatment on compound action potentials of the superior laryngeal nerve (SLN) afferents were studied in 6 sevoflurane-anesthetized dogs. Perineural CAPS (100 μg/ml) to the bilateral SLNs reduced (P<0.01) the peak and integral amplitudes of the C-wave of the compound action potential. By contrast, the perineural CAPS had no effect on the A-wave component (P>0.05). Removal of the perineural CAPS recovered the C-wave to pretreatment level. The perineural CAPS treatment selectively blocks C-wave compound action potentials of the SLN afferents, providing a useful tool for studies of laryngeal C-fibers in respiratory physiology.
- 公益社団法人 日本獣医学会の論文
著者
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Kojima Kentaro
Department Of Mechanical Systems Engineering Faculty Of Engineering Kanazawa University
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Tsubone Hirokazu
Department Of Comparative Pathophysiology Graduate School Of Agricultural And Life Science The Unive
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Sasaki Nobuo
Department Of Pharmacology Faculty Of Veterinary Medicine Hokkaido University
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Kanamaru Arata
Department Of Physiology Showa University School Of Medicine
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NISHIMURA Ryohei
Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo
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MUTOH Tatsushi
Division of Cardiovascular Medicine and Department of Pediatrics, University of California, Davis, CA 95616, USA.
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Sasaki Nobuo
Department of Biological Science and Technology, Tokyo University of Science
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TSUBONE Hirokazu
Department Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
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SASAKI Nobuo
Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
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KANAMARU Arata
Department Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
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