Influence of Methylproline Isomers upon Neoviridogrisein Synthesis
スポンサーリンク
概要
- 論文の詳細を見る
Influence of positional and stereoisomers of methylproline on the biosynthesis of neoviridogrisein (NVG) by Streptomyces griseoviridus P8648 was investigated. 3-(DL-cis+trans)- and 5-(D-cis+L-trans)-Methylprolines inhibited NVG synthesis, but they did not affect the cell growth. When these imino acids were added to cultures of S. griseoviridus P8648, there occurred no production of NVG homologues. In the presence of 4-methylproline (D-cis+L-trans), the organism synthesized a new NVG, designated NVG-MP, in which the imino acid moiety was replaced by 4-methylproline (D- cis). The antimicrobial activity of NVG-MP was compared with those of NVG II and viridogrisein (VG).
- 社団法人 日本農芸化学会の論文
著者
-
Fukagawa Yasuo
Central Research Laboratories Sanraku Incorporated
-
Okamoto Rokuro
Central Research Laboratories Mercian Corporation
-
Okumura Yasushi
Central Research Laboratories Asahi Breweries Ltd.
-
Ishikura Tomoyuki
Central Research Laboratories Sanraku Incorporated
-
OKUMURA Yasushi
Central Research Laboratories, Sanraku-Ocean Co.
-
ISHIKURA Tomoyuki
Central Research Laboratories, Sanraku-Ocean Co.
-
FUKAGAWA Yasuo
Central Research Laboratories, Sanraku-Ocean Co.
関連論文
- Isolation of Methanol-assimilating Bacteria and Optimum Medium Composition
- Production of Recombinant Mite Allergen Der fI in Insect Cells and Characterization of Products : Removal of Pro-sequence Is Essential to IgE-Binding Activity
- Cloning and Expression of cDNA Coding for the Major House Dust Mite Allergen Der f II in Escherichia coli(Biological Chemistry)
- A New Type of Streptomycete Arylsulfatase with High Affinity to the Sulfuryl Moiety of the Substrate
- Arylsulfatase from Streptomyces griseorubiginosus S980-14
- Screening and Production of Arylsulfatases for Target Therapy with Etoposide 4'-Sulfate,an Antitumor Prodrug
- Development of an Integrative DNA Transformation System for the Yeast Hansenula anomala
- Oxidative Decarboxylations of 4-Hydroxymandelic Acid and 2-(4-Hydroxyphenyl)glycine by Laccase from Coriolus versicolor and Bilirubin Oxidases from Trachyderma tsunodae and Myrothecium verrucaria
- Transformation of 7-(4-Hydroxyphenylacetamido)cephalosporanic Acid into a New Cephalosporin Antibiotic, 7-[1-Oxaspiro(2.5)octa-6-oxo-4, 7-diene-2-carboxamido]ceph-alosporanic Acid, by Laccase
- Coriolus versicolor Laccase Catalyzes the Decarboxylation of 2-(4-Hydroxyphenyl)-glycine and 4-Hydroxymandelic Acid
- Preferential Production of a Carbapenem Antibiotic, PS-5 by Dissolved Oxygen Controlled Fermentation
- Application of Cyclodextrin to Microbial Transformation of Vitamin D_3 to 25-Hydroxyvitamin D_3 and 1α, 25-Dihydroxyvitamin D_3
- Preferential and High-Yield Production of a Cephamycin C by Dissolved Oxygen Controlled Fermentation
- Flow Characteristic Simulation for Tower Fermentor With Two-fluid Nozzle : Studies on Biomass Production from Methanol (V)
- Growth Characteristics of Marine Methanol-utilizing Bacteria : Studies on Marine Methanol-utilizing Bacteria(II)
- Fermentative Production of Deltamycin and Deacyldeltamycin : Presented at the Annual Meeting of the Society of Fermentation Technology of Japan, Osaka, October 25,1976.
- Siamycins I and II, New Anti-HIV Peptides:I.Fermentation, Isolation, Biological Activity and Initial Characterization
- Deacetylation of PS-5,a New β-Lactam Compound-3-Enzymological Characterization of L-Amino Acid Acylase and D-Amino Acid Acylase from Pseudomonas sp. 1158
- Deacetylation of PS-5,a New β-Lactam Compound-2-Separation and Purification of L- and D-Amino Acid Acylases from Pseudomonas sp. 1158
- Enhanced Production of Antibiotics by Pecilomyces lilacinus under Alkaline Conditions Associated with Morphological Change(Microbiology & Fermentation Industry)
- Isolation and Characterization of Marine Methanol-utilizing Bacteria : Studies on Marine Methanol-utilizing Bacteria(I)
- New Anthracycline Antibiotic CG12 Obtained by Microbial Glycosidation of α-Citromycinone
- IMMUNOLOGICAL CROSS-REACTIVITIES OF VARIOUS ANTHRACYCLINE ANTIBIOTICS AGAINST ACLACINOMYCIN A ANTISERA
- An Improved Radioimmunoassay for Guanosine-5 -diphosphate-3 - diphosphate (ppGpp) and Its Application to Search for ppGpp in Rat Embryo and Brain
- Neoviridogrisein-Cls, NewAnalogs of Viridogrisein, Produced under the Supplementation of 4-Chloro-L-proline
- Carbon Catabolite Regulation of Neoviridogrisein Production by Glucose
- A Possible Biosynthetic Precursor of 3-Hydroxypicolinic Acid in Etamycin
- Influence of Methylproline Isomers upon Neoviridogrisein Synthesis
- A Certain Mutant Blocked in trans-4-Hydroxy-L-proline Formation from L-Proline during Neoviridogrisein Biosynthesis
- Some Effectors on the Biosynthesis of cis-4-Hydroxy-D-proline in Viridogrisein
- Determination of CGTase from Bacillus ohbensis and Its Optimum pH Using HPLC