Structure and Hypotensive Effect of Flavonoid Glycosides in Citrus unshiu Peelings
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概要
- 論文の詳細を見る
An attempt was made to isolate hypotensive substances from a hot water extract of Citrus unshiu. Six flavonoid glycosides were isolated by repeated chromatography and gel nitration after extraction with butanol and treatment with lead subacetate. Their structures were established to be limocitrin 3-β-D-glucose (1), limocitrin-3-α-L-rhamnose (2), 3, 6-di-C-glucosylapigenin (3), narirutin (4), rutin (5) and narcissin (6) by UV, 1H-NMR and 13C-NMR spectroscopy and sugar analysis. Each component was intravenously injected into SHR-SP rats (1 mg/100 g body weight), and 3 and 5 were found to lower their blood pressure. Among these compounds, 2 and 3 were a new flavonol and flavone glycoside, respectively.
- 社団法人 日本農芸化学会の論文
著者
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Murakami Tetsuo
Research Institute Of Food Science Kinki University
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OKAMOTO Kozo
Kinki University School of Medicine
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Iizuka Yoshitomi
Research Institute Of Food Science Kinki University
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MATSUBARA Yoshiharu
Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University
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Kumamoto Hiroyasu
Department of Applied Chemistry, Kinki University School of Science and Technology
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Yokoi Katsumi
Japan Sangaria beverage Co., Ltd.
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MIYAKE Hideo
Kinki University School of Medicine
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KUMAMOTO Hiroyasu
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University
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