Influence of Carbon Dioxide Partial Pressure on pH in Submerged Cultures
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概要
- 論文の詳細を見る
Bacillus subtilis AJ 3250 is capable of accumulating a remarkable amount of α-amylase in the culture liquid on pH-stat submerged fermentation. This microorganism requires sufficient oxygen as in other aerobic fermentations, and amylase production can only reach the maximum when the agitation and aeration conditions maintain the dissolved oxygen concentration above the critical level in pH controlled cultures. However, in pH uncontrolled cultures, amylase production as well as cell mass activity increase under low aeration conditions such as 1/20 vvm. Studies were carried out to analyse this phenomenon, and some new ways to express the relationship between the behaviour of pH and that of carbon dioxide partial pressure in a culture system were introduced. In this study, it was found that the differentiation in the carbon dioxide evolution rate reflects the dynamic characteristics of the pH change in this type of fermentation. An appropriate method of neutralization for managing pH-stat cultures on submerged fermentation can be obtained using this theory.
- 社団法人 日本農芸化学会の論文
著者
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Shibai Hiroshiro
Central Research Laboratories Ajinomoto Co. Inc.
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SHIBAI Hiroshiro
Central Research Laboratories of Ajinomoto Co.
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IKEDA Shigeho
Central Research Laboratories of Ajinomoto Co.
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HIROSE Yoshio
Central Research Laboratories of Ajinomoto Co.
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ISHIZAKI Ayaaki
Central Research Laboratories of Ajinomoto Co.
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