Staurosporine-induced Differentiation in a Human Neuroblastoma Cell Line, NB-1
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概要
- 論文の詳細を見る
A new differentiation screening system employing a human neuroblastoma cell line. NB-1, was used to isolate staurosporine as an inducer obtained from the culture broth of Streptomyces actuosus. Staurosporine at a concentration of 20 nM induced elongation of neurites and cell enlargement one hour after treatment of NB-1. In addition, the agent had a cytotoxic effect against NB-1 at a concentration of more than 0.21 μM.
- 社団法人 日本農芸化学会の論文
著者
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SUZUKI Toshimitsu
Department of Chemical Engineering
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Morioka Hajimu
Central Research Laboratories Ajinomoto Co. Jnc.
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Shibai Hiroshiro
Central Research Laboratories Ajinomoto Co. Inc.
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SHIBAI Hiroshiro
Central Research Laboratory, Ajinomoto Co., Inc.
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ISHIHARA Masaru
Central Research Laboratories of Ajinomoto Co. Inc.
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ISHIHARA Masaru
Central Research Laboratory, Ajinomoto Co., Inc.
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