Effect of Oxygen Supply on L-Valine Fermentation

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概要

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• The effect of oxygen tension on L-valine fermentation was investigated using a valine-producing mutant of Brevibacterium lactofermentum, a glutamate producer.The product formation was maximal when the rate of oxygen supply was limited so that cell respiration was slightly inhibited to give a value of r_<ab>/KrM (rate of cell respiration/rate of cell's oxygen demand) 0.5-0.7. The E level (thr redox potential of the medium, mV) was between -260 and -200 mV in this culture, suggesting that E is a useful index to oxygen tension during the fermentation. This observation corresponds to the characteristics of the biosynthesis, where a precursor of L-valine, α-ketoisovalerate, is anaerobically produced.

• 公益社団法人日本生物工学会の論文
• 1977-08-25

著者

• Hirose Yoshio

  Central Research Laboratories Of Ajinomoto Co. Inc.

• Shibai Hiroshiro

  Central Research Laboratories Ajinomoto Co. Inc.

• Shibai Hiroshiro

  Central Research Laboratories Of Ajinomoto Co. Inc.

• AKASHI KUNIHIKO

  Central Research Laboratories of Ajinomoto Co., Inc.

• Akashi Kunihiko

  Central Research Laboratories Of Ajinomoto Co. Inc.

• HIROSE Yoshio

  Central Research Laboratories of Ajinomoto Co.

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