OS0907 ソフトマテリアルに播種された細胞の伸展に対する適合性(OS9-2 生体機能・材料(細胞),OS-9 生体機能・材料)

概要

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In addition with medical materials, those involving cells are applied for tissue engineering recently. Cells involved in those medical materials experience physical dynamics after implantations. If the medical material exhibits high elasticity, cells would experience soft physical dynamics. However, if the medical material exhibits low elasticity, cells would experience hard physical dynamics. Medical materials with low elasticity are targeted to be used for high bio-compatibility and bio-absorbability. However, it is obscure whether cells on those medical materials with low elasticity could bear the hard physical dynamics after implantations. In this study, cells spread on soft material were stretched to investigate whether those cells could conserve physical structure even after the stretch. To evaluate conservation of the physical structure, stress fibers are visualized with GFP-actin. Furthermore, traction force was compared before and after the stretch.
一般社団法人日本機械学会の論文
2011-07-16