217101 細胞間コミュニケーションに現れる1/fゆらぎのモデリング(OS07 細胞・生体組織1,オーガナイズド・セッション)

概要

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1/f fluctuations, the power spectrum of signals inversely proportional to the frequency, have been observed in various types of physiological systems. However, the mechanism of fluctuations is not fully disclosed so far. In our study, we focused our attention on 1/f fluctuations appear in non-equilibrium ions concentration in cells, and built a phenomenological model of ions transport performed by ions channels transport and diffusion between cells. We conducted numerical analysis using the proposed model. Results predicted that individual cells are needed to have different abilities of ions diffusion, those were assumed to independently function for each cells in the present model, to generate 1/f fluctuations. Ions diffusion via cellular communication plays a key role in ions transport dynamics of cells accompanying 1/f fluctuations.
一般社団法人日本機械学会の論文
2011-03-17