生薬の品質評価に関する研究(第7報) : Sephadex Columnによる決明子中anthraquinoneの分離と定量

概要

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The separation and the quantitative estimation of anthraquinones in Ketsumeishi samples from various places was carried out by using Sephadex LH-20 column chromatography. The anthraquinone extracts produced, on the column, a number of well separated brown-yellow coloured zones during elution. The best separation was obtained by using 70% methanol as eluent. Chrysophanol, obtusin, aurantio-obtusin, chryso-obtusin, obtusifolin, emodin, aloe-emodin, physcion and their glycosides were shown to be present in the extract of the seed of Cassia obtusifolia L., but obtusifolin, chryso-obtusin and their glycosides were not detected in C. tora L. Of these anthraquinones, chrysophanol diglycoside and aurantioobtusin monoglycoside were the main components. Thus the crude drug, Ketsumeishi, from different places may be classified into three groups according to the constitution and contents of their anthraquinone fractions.
日本生薬学会の論文
1978-12-20