生薬の品質評価に関する研究(第2報) : 朮類生薬成分のTLC, GCおよびGC-MSによる確認とその理化学的品質評価

概要

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Chemotaxonomical differentiation of the origin of Atractylodes rhizomes was attempted by the use of thin-layer chromatography, gas chromatography and gas chromatography-mass spectrometry. Ten constituents of Atractylodes rhizomes hitherto been identified such as atractylon, 3β-hydroxyatractylon, 3β-acetoxyatractylon, atractylodin, atractylodinol, acetylatractylodinol, hinesol, β-eudesmol, elemol, selina-4(14) ,7(11)-dien-8-one and three other unspecified substances in the hexane extracts were used for their differentiation. The presence of atractylodin, atractylodinol and acetylatractylodinol in the hexane extract was found to be specific for the three kinds of ATRACTYLODIS LANCEA RHIZOMA being defined in the Pharmacopoeia of Japan, and could be differentiated from the other two kinds of ATRACTYLODIS RHIZOMA. In addition to these, there were several differences in their ingredients in these five kinds, however, they were not specific enough to discriminate each other. Thus, it is likely to be necessary to make some additional morphological examination for the discrimination of Atractylodes rhizomes.
日本生薬学会の論文
1976-12-20