T0501-5-2 MEMSサーモパイルセンサによるnW級バイオカロリメトリの研究([T0501-5]マイクロ・ナノスケールの熱流体現象(5))

概要

論文の詳細を見る
The bio-calorimetry measures metabolic heat of living bodies such as cells, organs, insects, seeds and so on. However, conventional bio-calorimeter with a micro-watt resolution becomes insufficient for the latest highly analytical biochemistry. In this research, new bio-calorimeter with a nano-watt level metabolic heat resolution has been developed with MEMS thermopile sensors. It is important for high sensitive calorimeter to improve both sensitivity and noise reduction characteristics. The MEMS thermopile has high sensitivity of 2.6V/W. For noise reduction cased by the room temperature fluctuation, differential method and four-hold thermostat were used. An incubator was also newly introduced. As a result, the noise reduction characteristics was estimated at 10〜17nW to room temperature fluctuation under 0.5mHz. For the thermal analysis of Yeast, the metabolic heat generation over 20nW level was measured by excepting an initial settling behavior of the calorimeter.
2010-09-04