11602 エレクトロスピニング法を用いた組織再構築型層構造再生血管の開発(バイオエンジニアリング,一般講演,学術講演)

概要

論文の詳細を見る
It is said that compliance mismatch between a native vessel and a artificial vascular graft causes low patency after several years of implantation. To develop a vascular scaffold having a mechanical characteristics like native vessels, a bi-layered tubular scaffold composed of a porous CLLA inner layer and PLLA fibrous outer layer using electrospinning technique was fabricated. A porous CLLA scaffold was inserted to mandrel-type collector having larger diameters than inner that of CLLA tubular scaffold and PLLA was electrospun onto a pre-strained porous CLLA scaffold. In this study we researched relationships between wall thickness and each electrospinning conditions and effects of pre-straining on mechanical characteristics of fabricated multi-layered tubular scaffold.
社団法人日本機械学会の論文
2008-03-13