Felty症候群や肝硬変との鑑別を要した特発性門脈圧亢進症の1例

概要

論文の詳細を見る
We encountered a case of idiopathic portal hypertension (IPH) with anti-HCV-positive antibody and rheumatoid factor (RF). The case, a 58-year-old women, had been given a blood transfusion 25 years before and had been known to have sever leukopenia (900/μl), thrombocytopenia (3 × 10^4/μl) and marked splenomegaly for the past 15 years. At first, type C liver cirrhosis or Felty's syndrome was suspected. However, she had no rheumatoid arthritis clinically and HCV-RNA was not detected in serum by polymerase chain reaction, so we assumed that anti-HCV-positive antibody revealed merely past infection of HCV. We confirmed that her liver had no nodular surface by laparoscope. Based on our findings, we diagnosed her as IPH and differentiated from Felty's syndrome and type C cirrhosis. After Hassab's operation, WBC and platelet counts returned to normal range and histological features were consistent with IPH.
東京女子医科大学の論文
1996-12-25