Blood Pressure, Levels of Serum Lipids, Liver Enzymes and Blood Glucose by Aldehyde Dehydrogenase 2 and Drinking Habit in Japanese Men
スポンサーリンク
概要
- 論文の詳細を見る
Objectives: The association of blood pressure and levels of serum lipids, liver enzymes, blood glucose and aldehyde dehydrogenase 2 (ALDH2) with drinking habit was examined in Japanese men. Methods: The subjects were 264 men aged 39 to 80 years who were classified into the ALDH2 deficiency or sufficiency group using the ethanol patch test and the Tokyo University ALDH2 Phenotype Screening Test. A self-administered questionnaire including drinking habit was used. Blood pressure and the levels of biochemical markers in groups with ALDH2 sufficiency, ALDH2 deficiency and drinking habit were compared using multiple regression models for adjusting age, smoking habit, physical exercising habit and body mass index. Results: The levels of serum high-density lipoprotein cholesterol, triglycerides, aspartate aminotransferase (AST) and gamma-glutamyl transpeptidase (γ-GTP) were significantly higher in current drinkers of 20 g of ethanol or more per day than in nondrinkers of the ALDH2 sufficiency group. The levels of serum AST and γ-GTP in current drinkers of 20 g of ethanol or more per day, and fasting blood sugar in current drinkers of less than 20 g of ethanol per day were significantly higher than those in nondrinkers of the ALDH2 deficiency group. Conclusions: These results suggest that alcohol consumption increases the levels of serum lipids and liver enzymes in ALDH2-sufficient individuals and liver enzymes and blood glucose levels in ALDH2-deficient individuals.
- 日本衛生学会の論文
著者
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HASHIMOTO Shuji
Department of Physiologic Laboratory, National Cardiovascular Center
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ITO Yoshinori
Department of Public Health, Fujita Health University School of Health Sciences
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SUZUKI Koji
Department of Public Health, Fujita Health University School of Health Sciences
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Ito Yoshinori
Department Of Public Health Fujita Health University School Of Health Sciences
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Ito Yoshinori
札幌医科大学 医学部公衆衛生学
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橋本 周司
早稲田大学理工学術院 先進理工学研究科
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Hashimoto S
Department Of Hygiene Fujita Health University School Of Medicine
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Ito Yoshinori
Department Of Preventive Medicine/biostatistics And Medical Decision Making Nagoya University Gradua
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INABA Yutaka
Juntendo University School of Medicine
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Inaba Yutaka
愛知医科大学 公衆衛生学
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NAKAMURA Sayuri
Department of Adult Nursing, Fujita Health University School of Health Sciences
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Suzuki K
Department Of Public Health School Of Health Sciences Fujita Health University
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Nakamura Sayuri
Department Of Adult Nursing Fujita Health University School Of Health Sciences
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Inaba Y
Juntendo Univ. School Of Medicine
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Ishida Yoshiko
Department Of Preventive Medicine-biostatistics And Medical Decision Making Nagoya University Gradua
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Inaba Y
Department Of Physics University Of Tokyo
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橋本 周司
早稲田大学理工学研究科応用物理科
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Suzuki Koji
Department Of Public Health Fujita Health University Of Health Sciences
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Ito Yoshinori
Department Of Medical Oncology Cancer Institute Hospital Japanese Foundation For Cancer Research
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Inaba Y
Department Of Epidemiology And Environmental Health Juntendo University School Of Medicine
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Hashimoto Shuji
Department Of Applied Biological Chemistry Faculty Of Agriculture Niigata University
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Inaba Yutaka
Department Of Health And Environmental Sciences Graduate School Of Medicine Kyoto University
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Ito Yoshinori
Department Of Biomedical Food Research National Institute Of Infectious Diseasea(former National Ins
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Ito Yoshinori
Department Of Preventive Medicine - Biostatistics And Medical Decision Making Nagoya University Grad
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Suzuki Koji
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Ito Yoshinori
Department Of Biochemistry Nagoya City University Medical School
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Inoue Yusuke
Department Of Health And Environmental Sciences Graduate School Of Medicine Kyoto University
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Suzuki Koji
Department Of Orthopaedic Surgery Toride Kyodo General Hospital
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SUZUKI Koji
Department of Agricultural Chemistry, University of the Ryukyus
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