Association of Abdominal Circumference with Serum Nitric Oxide Concentration in Healthy Population

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概要

• 論文の詳細を見る

• Objectives: We determined the relationship between abdominal circumference and the concentration of nitric oxide (NO), an endothelial cell product known to play an important role in the regulation of vascular tone and thrombocyte activations. Methods: Subjects were 177 men and 339 women aged 40 or over who were free from a history of diabetes or malignancy. Analysis of covariance was applied to examine the gender-specific and smoking-status-specific associations of abdominal fat volume measured as waist circumference, waist-hip ratio, and waist-to-stature ratio, with serum NO level represented by the concentration of NO metabolites (NOx; nitrate plus nitrite). Results: Although men showed no statistical association between abdominal fat accumulation and NOx concentration, abdominal adiposity seemed to inversely affect the serum NOx concentration of never- and current-smoking women. Conclusion: Our results suggest that a reduction in NO bioactivity occurs with abdominal fat accumulation in women. The underlying biological mechanism might involve adipocytokines secreted from visceral fat, but is yet to be elucidated.

• 日本衛生学会の論文

著者

• ITO Yoshinori

  Department of Public Health, Fujita Health University School of Health Sciences

• SUZUKI Koji

  Department of Public Health, Fujita Health University School of Health Sciences

• Ito Yoshinori

  Department Of Public Health Fujita Health University School Of Health Sciences

• Ito Yoshinori

  札幌医科大学 医学部公衆衛生学

• KONDO Takaaki

  Department of Medical Technology, Nagoya University School of Health Sciences

• Kondo Takaaki

  Department Of Cardiology Nagoya University Graduate School Of Medicine

• Ito Yoshinori

  Department Of Preventive Medicine/biostatistics And Medical Decision Making Nagoya University Gradua

• INABA Yutaka

  Juntendo University School of Medicine

• Inaba Yutaka

  愛知医科大学 公衆衛生学

• Imai Ryota

  Department of Medical Technology, Nagoya University School of Health Sciences

• Ueyama Jun

  Department of Medical Technology, Nagoya University School of Health Sciences

• Suzuki K

  Department Of Public Health School Of Health Sciences Fujita Health University

• Kadowaki Takashi

  滋賀大学 医学部健康科学科

• Inaba Y

  Juntendo Univ. School Of Medicine

• Ueyama Jun

  Department Of Medical Technology Nagoya University School Of Health Sciences

• Ueyama Jun

  名城大学 薬学部薬剤学研究室

• Ishida Yoshiko

  Department Of Preventive Medicine-biostatistics And Medical Decision Making Nagoya University Gradua

• Inaba Y

  Department Of Physics University Of Tokyo

• Takagi Kenzo

  Third Division Of The Research Laboratory For Development Of Medicine School Of Pharmacy Hokuriku Un

• Suzuki Koji

  Department Of Public Health Fujita Health University Of Health Sciences

• Ueyama Jun

  Department Of Medicinal Informatics Graduate School Of Medical Science Kanazawa University ; Departm

• Ito Yoshinori

  Department Of Medical Oncology Cancer Institute Hospital Japanese Foundation For Cancer Research

• Inaba Y

  Department Of Epidemiology And Environmental Health Juntendo University School Of Medicine

• Ueyama Jun

  Department Of Medical Technology Nagoya University School Of Health Science

• Imai Ryota

  Department Of Medical Technology Nagoya University School Of Health Sciences

• Inaba Yutaka

  Department Of Health And Environmental Sciences Graduate School Of Medicine Kyoto University

• Ito Yoshinori

  Department Of Biomedical Food Research National Institute Of Infectious Diseasea(former National Ins

• Ito Yoshinori

  Department Of Preventive Medicine - Biostatistics And Medical Decision Making Nagoya University Grad

• Suzuki Koji

  Department Of Applied Chemistry Faculty Of Science And Technology Keio University

• Ito Yoshinori

  Department Of Biochemistry Nagoya City University Medical School

• Ito Yoshinori

  Department Of Preventive Medicine/biostatistics And Medical Decision Making Nagoya University Gradua

• Inoue Yusuke

  Department Of Health And Environmental Sciences Graduate School Of Medicine Kyoto University

• Suzuki Koji

  Department Of Orthopaedic Surgery Toride Kyodo General Hospital

• INABA Yutaka

  Department of Physics, University of Tokyo

• SUZUKI Koji

  Department of Agricultural Chemistry, University of the Ryukyus

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