慢性甲状腺炎の臨床的研究(1) : 一過性の甲状腺機能亢進症を呈した慢性甲状腺炎

概要

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Transient hyperthyroidism was observed in 7 patients with chronic thyroiditis and the following characteristic features were obtained. 1) All were female and their ages were between 18 and 62 year-old. 2) Hyperthyroidism was generally mild and lapsed in a rather short time. In 4 cases out of 7 cases hyperthyroidism subsides spontaneously. In the other 3 cases treated by antithyroid drug hyperthyroidism disappeared rapidly following a short duration of hypothyroid. 3) The thyroidal radioactive iodine uptake was extremely low except for moderately low value in 1 case at the first visit. After a recovery of hyperthyroidism the radioactive iodine uptake performed in 4 cases elevated to abnormaly high values. T_3 suppression test performed in 2 cases was both positive. 4) Serum ^<131>I-T_3 resin uptake, T_4 and PBI levels were all high and BMR was slightly elevated at the first visit. 5) Serum TSH level performed in 2 cases was both normal at the first visit. 6) Antithyroglobulin antibody was positive in all 7 cases. Antimicrosomal antibody was positive in 4 cases and negative in 2 cases. 7) ESR was within normal limits in 5 cases and was elevated in 2 cases at the first visit. 8) Serum γ-globulin level was elevated except for that in 1 case. 9) Serum LATS performed in 2 cases was both negative. 10) Histologic examination performed in 3 cases revealed the presence of chronic thyroiditis, with no feature of Graves's disease.
北里大学の論文
1976-02-29