Apoptosis-Inducing Activity of Lipid Derivatives of Gallic Acid
スポンサーリンク
概要
- 論文の詳細を見る
Gallic acid derivatives with a lipophilic group (hydrogenated farnesyl gallate, lauryl gallate, gallic acid laurylamide and cholesteryl gallate) were examined for their ability to induce apoptosis in human monoblastic leukemia U937 cells. Farnesyl ester derivative is the most potent apoptosis inducer among the compounds examined. The results suggest that lipid derivatives can augment the apoptosis-inducing activity of gallic acid depending on the structure. These findings will provide useful information in developing anti-cancer agents.
- 公益社団法人日本薬学会の論文
- 2000-11-01
著者
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Abe Ikuro
School of Pharmaceutical Sciences and the COE 21 Program, University of Shizuoka
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Noguchi Hiroshi
School of Pharmaceutical Sciences and the COE 21 Program, University of Shizuoka
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ISEMURA Mamoru
School of Food and Nutritional Sciences and Center of Excellence for the 21st Century, University of
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SAEKI KOUICHI
Department of Surgery I, Yamaguchi University School of Medicine
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YUO Akira
Department of Hematology, Research Institute, International Medical Center of Japan
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SEKI Takahiro
School of Pharmaceutical Sciences, University of Shizuoka
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Abe Ikuro
School Of Pharmaceutical Sciences And The Coe 21 Program University Of Shizuoka:presto Japan Science
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Saeki Kouichi
Department Of Hematology Research Institute International Medical Center Of Japan
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伊勢村 護
Cellular Biochemistry School Of Food And Nutritional Sciences University Of Shizuoka
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Isemura Mamoru
Laboratory Of Cellular Biochemistry Graduate School Of Nutritional And Environmental Sciences Univer
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Yuo Akira
Department Of Hematology Research Institute International Medical Center Of Japan
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Seki Takahiro
School Of Information Science Japan Advanced Institute Of Science And Tchnology Hokuriku
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Noguchi Hiroshi
School Of Pharmaceutical Sciences And The Coe 21 Program University Of Shizuoka
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