STIMULATIVE EFFECTS OF CORTISOL AND TESTOSTERONE ON BILE CALCIUM EXCRETION IN THYROPARATHYROIDECTOMIZED RATS
スポンサーリンク
概要
- 論文の詳細を見る
The effects of cortisol and testosterone on calcium metabolism in the hepatic bile system were investigated in thyroparathyroidectomized rats. A single subcutaneous administration of cortisol (0.1 mg/100 g) or testosterone (0.1 mg/100 g) caused a significant fall in serum calcium and a corresponding increase in liver calcium. On the other hand, the excretion of calcium into the bile after a single intraperitoneal injection of calcium chloride (4.0 mg Ca/100 g) was markedly increased by the administration of cortisol (0.1 and 1.0 mg/100 g) or testosterone (0.1 and 1.0mg/100 g). However, the bile calcium excretion was not significantly altered by the administration of thyroxine (0.1 and 1.0 mg/100 g) or vitamin D_3 (20 and 100 μg/100 g). The present results suggest that the hypocalcemic effect of cortisol or testosterone is partly based on the stimulation of calcium excretion into the bile by the hormones.
- 公益社団法人日本薬学会の論文
著者
-
Okada Shoji
Department of Radiobiochemistry, School of Pharmaceutical Sciences, University of Shizuoka
-
YAMAGUCHI Masayoshi
Department of Legal Medicine, Kinki University School of Medicine
-
Okada Shoji
Department Of Environmental Biochemistry Shizuoka College Of Pharmacy
-
Yamaguchi Masayoshi
Department Of Environmental Biochemistry Shizuoka College Of Pharmacy
-
AKIYAMA YOSHIZO
Department of Environmental Biochemistry, Shizuoka College of Pharmacy
-
Akiyama Yoshizo
Department Of Environmental Biochemistry Shizuoka College Of Pharmacy
-
Okada Shoji
Department Of Environmental Biochemistry Shizoka College Of Pharmacy
-
Yamaguchi Masayoshi
Department Of Electrical Engineering Nagaoka University Of Technology
-
YAMAGUCHI Masayoshi
Department of Environmental Biochemistry, Shizuoka College of Pharmacy
関連論文
- Deuteration Causes the Decreased Induction of Heat-Shock Proteins and Increased Sensitivity to Heat Denaturation of Proteins in Chlorella : ENVIRONMENTAL AND STRESS RESPONSES : PROTEINS, ENZYMES AND METABOLISM
- Characteristics of the Photosynthetic Metabolism of Carbon in Deuterated Chlorella ellipsoidea C-27
- Differential Cellular Isotope Effects of Deuterium on Photosynthetic Metabolism of Carbon in Chlorella ellipsoidea
- Standard weight of the normal brain, spleen and pancreas in Japanese
- Autopsy Cases of Giant Heart during the Past Ten Years in Osaka(1985-1994)
- Estimation of Age from Soft X-ray Findings of Japanese Females Thyroid Cartilages
- Estimation of Age from Image Processing of Soft X-ray Findings in Japanese Male Thyroid Cartilages
- Sexual discrimination on the soft X-ray findings of Japanese thyreoideal cartilages
- Changes in chromium concentration in organs of Japanese
- Changes in human liver weight in forensic autopsy cases between 1962 and 1992
- Effect of Growth Temperature on the Response of Cells to Mating Hormones in Saccharomyces Cerevisiae
- Increased Expression of Hsp70 for Resistance to Deuterium Oxide in a Yeast Mutant Cell Line
- Effect of Over-Expressed Hsp26 on Cell Growth of Yeast
- Role of Hsp70 Subfamily, Ssa, in Protein Folding in Yeast Cells, Seen in Luciferase-Transformed ssa Mutants
- Chaperonin-Repairable Subtle Incompleteness of Protein Assembly Induced by a Substitution of Hydrogen with Deuterium : Effect of GroE on Deuterated Ribulose 1,5-Bisphosphate Carboxylase : PROTEINS, ENZYMES AND METABOLISM
- TUMOR ACCUMULATION OF D-SELENOMETHIONINE-^Se IN TUMOR-BEARING MICE
- Alterations in the Heat Response of Chlorella ellipsoidea by Deuteration
- Role of Transferrin in Manganese Transport into the Brain (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
- Brain Uptake of the Trace Metals, Zinc and Manganese, in Rats (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Role of Sialylglycoconjugate(s) in the Initial Phase of Metastasis of Liver-metastatic RAW117 Lymphoma Cells
- Growth Delay and Intracellular Changes in Chlorella ellrpsoidea C-27 as a Result of Deuteration : GROWTH AND DEVELOPMENT : STRUCTURE AND FUNCTION OF CELLS
- Influence of Histidine on Zinc Transport into Rat Brain
- Transport and Action of Cadmium and Zinc in Rat Brain(PROCEEDINGS OF 24TH SYMPOSIUM ON TOXICOLOGY AND ENVIRONMENTAL HEALTH)
- Autitumor Activity of 5'-O-Dipalmitoylphosphatidyl 2'-C-Cyano-2'-deoxy-1-β-D-arabino-pentofuranosylcytosine Is Enhanced by Long-Circulating Liposomalization
- Application of Long-Circulating Liposomes to Cancer Photodynamic Therapy
- Effect of Freeze-Thawing on Phospholipid/Surfactant Mixed Bilayers
- Permeability Change of Liposomal Membrane Induced by Interleukin-1∂
- Manganese Transport in Blood-Cerebrospinal Fluid Barrier and Its Intracerebral Transport (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
- Effect of Inorganic and Methylated Arsenics on E. coli Genes (Regular Presentations) (Proceedings of the 10 th Symposium on Environmental Pollutants and Toxicology)
- EFFECT OF INORGANIC ARSENICS ON CYTOTOXICITY AND MUTAGENICITY OF ULTRAVIOLET LIGHT ON ESCHERICHIA COLI AND THE MECHANISM INVOLVED
- Effect of Chromium (III) on RNA Synthesis in Mouse Liver and Regenerating Rat Liver (Regular Presentations) (Proceedings of the 9th Symposium on Environmental Pollutants and Toxicology)
- STIMULATORY EFFECT OF ZINC ON BONE GROWTH IN WEANLING RATS
- STIMULATION OF BONE RESORPTION BY COMPARATIVELY HIGH DOSE OF ZINC IN RATS
- STIMULATIVE EFFECTS OF CORTISOL AND TESTOSTERONE ON BILE CALCIUM EXCRETION IN THYROPARATHYROIDECTOMIZED RATS
- INTERACTION OF CALCITONIN AND HISTAMINE ON BILE CALCIUM EXCRETION IN THYROPARATHYROIDECTOMIZED RATS
- Participation of Hsp72 in DNA Damage by Dimethylarsenics : Possible Relationship between Hsp72 and Apoptosis Induced in Pulmonary Cultured Cells (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
- Involvement of Metabolic Methylation in Arsenic-Induced Mutagenesis for Mammalian Cells (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
- Differential Effect of UV-B and UV-C on DNA Damage in L-132 Cells
- Mode of Gene Damage Induced by Exposure to UVB and Some Radical Species (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Interaction between Dimethylarsenics and Active Oxygen Species in the Induction of Gene Damage (Proceedings of the 19th Symposium on Toxicology and Environmental Health)
- Structure and Non-Equilibrium Phase Diagram of the Co-Sputtered and Post-Annealed Fe-ZnO System
- Stimulatory Effect of Calcitonin on Bone Formation in Tissue Culture
- THE STIMULATORY ROLE OF ZINC IN BONE METABOLISM OF WEANLING RATS
- Brain Distribution of Zinc and Manganese and Their Biological Half-Lives in Rat (Proceedings of the 21st Symposium on Toxicology and Environmental Health)
- Metallothionein Induction in Rat Brain after Intrastriatal Injection of Zinc and Cadmium Salts(PROCEEDINGS OF 24TH SYMPOSIUM ON TOXICOLOGY AND ENVIRONMENTAL HEALTH)
- ROLE OF SERUM ALBUMIN AND ITS MERCAPTO-NONMERCAPTO CONVERSION IN TUMOR TRANSPORT OF ^Tc-HOMOCYSTEINE, A POSSIBLE TUMOR-IMAGING AGENT
- Trinuclear Complexes Containing Incomplete Cubane Co^_3O_4 Cores. Structures of the Isomers of the N-(2-Pyridylmethyl)glycinato Complex
- 116. Fundamental Studies on Mechanism of Toxic Action by Tin. : Correlation Between the Accumulated Calcium in Kidney and the Decreased Calcium in Serum, Part II. (The Second Meeting for the Study of Toxic Effect)
- 115. Fundamental Studies on Mechanism of Toxic Action by Tin. : Accumulation of Calcium in Kidney, Part I. (The Second Meeting for the Study of Toxic Effect)
- INHIBITION OF COLLAGEN SYNTHESIS IN THE FEMUR OF RATS ORALLY ADMINISTERED STANNOUS CHLORIDE
- CHANGES OF MINERAL COMPOSITION AND ITS RELATED ENZYME ACTIVITY IN THE FEMUR OF RATS ORALLY ADMINISTERED STANNOUS CHLORIDE
- ACTION OF INORGANIC TIN ON BONE METABOLISM IN RATS : DECREASES IN CALCIUM CONTENT AND PHOSPHATASE ACTIVITY
- Synthetic [Asu1, 7] Eel Calcitonin Increases Phosphorus Content in the Hepatic Bile of Intact and Nephrectomized Rats
- POSSIBLE MECHANISM OF TIN TO DECREASE CALCIUM CONTENT IN THE FEMUR OF RATS (The 6th Meeting for the Study of Toxic Effect)
- TARGET ORGAN OF INORGANIC TIN AND ITS NO-EFFECT LEVEL IN RATS
- HYPOCALCEMIC EFFECT OF ZINC AND ITS MECHANISM IN RATS
- CALCITONIN AND HEPATIC GLUCOSE OUTPUT : ROLE OF CELLULAR CALCIUM
- The Action of Zinc on Calcium Metabolism and Its Mechanism in Rats (Regular Presentations) (Proceedings of the 9th Symposium on Environmental Pollutants and Toxicology)
- CHANGES OF METALLOTHIONEIN LEVEL AND DISTRIBUTION OF RADIOACTIVE METALS IN TISSUES OF EXPERIMENTAL DISEASE MODEL ANIMALS
- EFFECT OF ZINC ON THE MITOCHONDRIAL FUNCTION IN THE LIVER OF RATS
- Alteration of Sodium Balance Following Administrations of Lead and/or Ethanol to Rats (Regular Presentations) (Proceedings of the 10 th Symposium on Environmental Pollutants and Toxicology)
- MECHANISMS OF POTENTIATION OF ANTITUMOR ACTIVITY OF 5-FLUOROURACIL BY RIBOTHYMIDINE IN A MOUSE TUMOR SYSTEM
- ENHANCEMENT OF ANTITUMOR ACTIVITY OF 5-FLUOROURACIL BY RIBOTHYMIDINE
- FUNDAMENTAI STUDIES ON MECHANISM OF TOXIC ACTION BY TIN. INCREASE OF BILE CALCIUM. PART VI (The Fourth Meeting for the Study of Toxic Effect)
- 225. FUNDAMENTAL STUDIES ON MECHANISM OF TOXIC ACTION BY TIN. DECREASE OF GASTRIC SECRETION. PART IV (The Third Meeting for the Study of Toxic Effect)
- ACTION OF TIN ON CALCIUM METABOLISN IN ENTEROHEPATIC SYSTEM (The 5th Meeting for the Study of Toxic Effect)
- Alteration in Bone Metabolism with Increasing Age : Effects of Zinc and Vitamin D_3 in Aged Rats
- Effects of Calcitonin and Other Hormones on Bile Calcium Excretion in Thyroparathyroidectomized Rats
- Reversible Effect of Calcium-Binding Protein on the Ca^-Induced Activation of Succinate Dehydrogenase in Rat Liver Mitochondoria(Biological)
- Effect of Calcitonin on Ca-ATPase Activity of Plasma Membrane in Liver of Rats
- Movement of Subcellular Calcium in Bile Pool of Hepatocyte in Rats: Effect of Thyroparathyroidectomy
- Calcitonin Increases Pyruvate Carboxylase Activity in Hepatic Mitochondria of Rats
- Regulatory Effect of Endogenous Calcitonin on Calcium Metabolism in Hepatic Bile System of Rats
- Comparison of Calcitonin, Epinephrine and Glucagon Effects on Plasma Membrane Ca-ATPase Activity and Calcium Content in Liver of Rats
- Calcitonin Stimulates Gluconeogenesis in Fasted Rats
- Effect of Parathyroid Hormone on the Increase in Serum Glucose and Insulin Levels After a Glucose Load to Thyroparathyroidectomized Rats
- Calcitonin Stimulates Glycogenolysis in the Liver of Fasted Rats
- Effect of Calcitonin on Calcium Concentration in Serum and Liver of Rats Ligated Bile Duct
- Preparation of CuGaS_2/ZnS Structures on GaAs(100) Substrate by Pulsed Excimer-Laser Deposition
- Calcitonin Increases Calcium Content and Phosphorylase a Activity in the Hepatic Particulate Glycogen of Rats