Effect of Over-Expressed Hsp26 on Cell Growth of Yeast
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概要
- 論文の詳細を見る
Mammalian small heat shock protein (s-hsp) has been suggested to participate not only in stress tolerance but also in the growth regulation and differentiation of cells. To confirm the role of s-hsp in cell growth, we investigated the relationship between the expression of hsp26 and yeast cell growth. Cells lacking constitutive hsp70,ssa1ssa2,have been known to have a poor growth rate and to over-express hsp26 and some other hsps. We obtained several cell clones of ssa1ssa2 whose doubling times were different from one another. The amount of hsp26 was closely linked to the doubling time of ssa1ssa2 cells. This result suggests that the expression of hsp26 modulates the growth rate of yeast cells lacking constitutive hsp70,similarly to mammalian cells.
- 社団法人日本薬学会の論文
- 1998-06-15
著者
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Unno K
Department Of Medical Biochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Unno Keiko
静岡県立大学 薬 医薬生命化学
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Unno Keiko
Department Of Radiobiochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Okada Shoji
Department of Radiobiochemistry, School of Pharmaceutical Sciences, University of Shizuoka
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KISHIDO Takahiro
Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka
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Okada S
Department Of Medical Biochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Okada S
Department Of Radiobiochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Okada S
Tokyo Medical Univ. Tokyo
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Okada S
Kumamoto Univ. Kumamoto Jpn
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Okada S
Univ. Shizuoka Shizuoka Jpn
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Okada Shoji
Department Of Environmental Biochemistry Shizuoka College Of Pharmacy
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Unno Keiko
Department Of Radiobiochemistry School Of Pharmaceutical Sciences
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Unno K
Univ. Shizuoka Shizuoka Jpn
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Kishido Takahiro
Department Of Medical Biochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Okada Shoji
Department Of Environmental Biochemistry Shizoka College Of Pharmacy
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Unno Keiko
Department Of Medical Biochemistry School Of Pharmaceutical Sciences University Of Shizuoka
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Okada Shoji
Department of Chemistry, Faculty of Science and Technology, Kinki University
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