Studies on the Structure of Polysaccharides from the Bark of Melia azadirachta
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概要
- 論文の詳細を見る
Water-soluble polysaccharides, designated as GIa and GIb, were isolated from the bark of Melia azadirachta (Meliaceae) and their inhibiting effect on subcutaneously inoculated Sarcoma-180 was tested. GIa and GIb each gave a single peak on ultracentrifugation and gel filtration. Methylation, periodate oxidation and ^<13>C-NMR spectroscopic studies suggested that GIa is composed of the following repeating unit ; α-D-Glc 1→4α-D-Glc 1→4α-D-Glc 1→4α-D-Glc 1→4α-D-Glc 6←1α-L-Araf. GIb is a branched arabinofucoglucan, containing a main chain of (1→4)-linked α-D-glucopyranosyl units substituted in the 6 position with side chains of α-L-arabinofuranosyl units. 3-O-substituted fucopyranose is attached to the α-(1→4) glucose units at the 4 position in the main chain.
- 社団法人日本薬学会の論文
- 1982-11-25
著者
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清水 正樹
テルモ(株)
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荻原 幸夫
Faculty of Pharmaceutical Sciences, Nagoya City University
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荻原 幸夫
Faculty Of Pharmaceutical Sciences Nagoya City University
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竹田 忠紘
Faculty Of Pharmaceutical Sciences Nagoya City University
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清水 正樹
Technical R and D Division, Terumo Co., Ltd.,
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野村 武男
Technical R and D Division, Terumo Co., Ltd.
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冨田 裕
Technical R and D Division, Terumo Co., Ltd.
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藤原 忠美
Faculty of Pharmaceutical Sciences, Nagoya City University
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野村 武男
Technical R And D Division Terumo Co. Ltd.
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冨田 裕
Technical R And D Division Terumo Co. Ltd.
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藤原 忠美
Faculty Of Pharmaceutical Sciences Nagoya City University
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Takeda T
Kyoritsu University Of Pharmacy
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