Polysaccharides of Lichens and Fungi. V. Antitumour Active Polysaccharides of Lichens of Evernia, Acroscyphus and Alectoria spp.

スポンサーリンク

概要

• 論文の詳細を見る

• The polysaccharides of some lichens were studied chemically in relation to their host-mediated antitumour activities against sarcoma 180 in mice. A water-insoluble polysaccharide fraction, EP-3,[α]^<17>_D +200°, from Evernia prunastri (L.) ACH. was shown to be an α-glucan containing α(1→3)(1→4) linkages in the ratio of 4 : 1. The cold water-soluble fraction, EP-4,was separated into EP-7,[α]^<17>_D +12°, and EP-6,[α]^<17>_D +164°. The former was shown to be an antitumour active glucan having β (1→3) (1→4) linkages in the ratio of 3 : 1,while the latter was revealed to be an α(1→3) (1→4) glucan (approx, ratio 3 : 2). The properties of these polysaccharides were discussed in comparing with the data of everniin reported by micovic, et al. A polysaccharide AS-3-IS, [α]^<14>_D+176°, isolated from Acroscyphyus sphaerophoroides LEV. giving an intensive blue iodine-colour reaction was shown to be a new type of α-glucan consisting of α(1→3), (1→4) and (1→6) linkages. A cold water-soluble polysaccharide, AS-3-S, was revealed to be a new glycopeptide. The polysacchrides, ASu-2 and ASa-2 isolated from Alectoria sulcata (LEV.) NYL. and A. sarmentosa (ACH.) ACH. were proved to be lichenin, and ASu-3 and ASa-3 were shown to be isolichenin. The host-mediated antitumour activities of the polysaccharide fractions isolated from the above lichen species were tested.

• 公益社団法人日本薬学会の論文
• 1972-11-25

著者

• 柴田 承二

  Faculty of Pharmaceutical Sciences, University of Tokyo

• 福岡 文子

  National Cancer Center Research Institute

• 柴田 承二

  Faculty Of Pharmaceutical Sciences University Of Tokyo:(present Address)meiji College Of Pharmacy

• 竹田 忠紘

  Faculty Of Pharmaceutical Sciences Nagoya City University

• 柴田 承二

  明治薬科大学

• 柴田 承二

  Faculty Of Pharmaceutical Sciences University Of Tokyo

関連論文

• Studies on the Water-soluble Constituents of Lichens. III. Changes in Antitumor Effect caused by Modifications of Pustulan- and Lichenan-type Glucans
• Chemical Studies on the Oriental Plant Drugs. XXXII. Sapogenins from the Roots of Platycodon grandiflorum A. DE CANDOLLE. (3). The Structure of a Prosapogenin, 3-O-β-Glucosylplatycodigenin
• Chemical Studies on the Oriental Plant Drugs. XXXI. Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE. (2). Structure of Platycodigenin
• Chemical Studies on the Oriental Plant Drugs. XXX. Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE. (1). Isolation of the Sapogenins and the Stereochemistry of Polygalacic Acid
• Chemical Studies on the Oriental Plant Drugs. XXIX. Saponins and Sapogenins of Ginseng : Further Study on the Chemical Properties of the Side Chain of Dammarane Type Triterpenes
• Chemical Studies on the Oriental Plant Drugs. XXVIII. Saponins and Sapogenins of Ginseng : Stereochemistry of the Sapogenin of Ginsenosides-Rb_1,-Rb_2 and -Rc
• Chemical Studies on the Oriental Plant Drugs. XXVII. The Acid Catalyzed Reactions and the Absolute Configuration at C_ of Dammarane Type Triterpenes
• Chemical Studies on the Oriental Plant Drugs. XXVI. Saponins and Sapogenins of Ginseng. The Absolute Configurations of Cinenic Acid and Panaxadiol
• Sapogenins of the Roots of Platycodon grandiflorum A. DE CANDOLLE and the Stereochemistry of Polygalacic Acid
• Chemical Studies on the Oriental Plant Drugs. XVII. The Prosapogenin of the Ginseng Saponins : Ginsenosides-Rb_1,-Rb_2,and -Rc
• Chemical Studies on the Oriental Plant Drugs. XVI. The Stereochemistry of Protopanaxadiol, a Genuine Sapogenin of Ginseng
• Chemical Studies on Oriental Plant Drugs. XIV. Protopanaxadiol, a Genuine Sapogenin of Ginseng Saponins
• Studies on the Constituents of Japanese and Chinese Crude Drugs. XII. Panaxadiol, A Sapogenin of Ginseng Roots. (2).
• Studies on the Constituents of Japanese and Chinese Crude Drugs. XI. Panaxadiol, A Sapogenin of Ginseng Roots. (1).
• Paeonolの生合成
• Studies on the Water Soluble Constituents of Lichens. II. Antitumor Polysaccharides of Lasallia, Usnea, and Cladonia Species
• The Structure of Isousnic Acid with Reference to "Isodihydrousnic Acid" derived from Dihydrousnic Acid
• Biosynthesis of Natural Products. VII. Biosynthesis of Usnic Acid in Lichens. Seasonal Variation observed in Usnic Acid Biosynthesis
• Biosynthesis of Natural Products. VI. Biosynthesis of Usnic Acid in Lichens. (1). A General Scheme of Biosynthesis of Usnic Acid
• Biosynthesis of Natural Products. III. Biosynthesis of Erythroskyrine, A Coloring Matter of Penicillium islandicum SOPP.
• Metabolic Products of Fungi. XXIV. The Structure of Erythroskyrine, a Nitrogen-containing Coloring Matter of Penicillium islandicum Sopp
• 牛蒡子の成分について
• 54 地衣共生体の分離とその代謝産物
• 9 Flavoskyrinの構造について
• Biosynthesis of Natural Products. V. Biosynthesis of Itaconitin. (2). Tracer Studies on Itaconitin
• Biosynthesis of Natural Products. IV. Biosynthesis of Itaconitin. (1). Degradation Studies on Itaconitin
• 10 Ephedrineの生合成
• Components of Stephanotis japonica MAKINO
• Polysaccharides of Lichen Symbionts
• Polysaccharides of Lichens and Fungi. VI. Antitumour Active Polysaccharides of Lichens of Stictaceae
• The Constituents of Pueraria Root
• Studies on the Saponins of Ginseng. II. Structures of Ginsenoside-Re, -Rf and -Rg_2
• Studies on the Saponins of Ginseng. I. Structures of Ginsenoside-Ro, -Rb_1,-Rb_2,-Rc and -Rd
• Chemical and Biochemical Studies on Carbohydrate Esters. II. Antitumor Activity of Saturated Fatty Acids and Their Ester Derivatives against Ehrlich Ascites Carcinoma
• Antitumor Polysaccharides from Some Polyporaceae, Ganoderma applanatum (PERS.) PAT and Phellinus linteus (BERK. et CURT) AOSHIMA
• Chemical and Biochemical Studies on Carbohydrate Esters. IX. Antitumor Effects of Selectively Fatty Acylated Products of Maltose
• Chemical and Biochemical Studies on Carbohydrate Esters. V. Anti Ehrlich Ascites Tumor Effect and Chromatographic Behaviors of Fatty Acyl Monoesters of Sucrose and Trehalose
• Chemical and Biochemical Studies on Carbohydrate Esters. III. Antitumor Activity of Unsaturated Fatty Acids and Their Ester Derivatives against Ehrlich Ascites Carcinoma
• Chemical Studies on the Oriental Plant Drugs. XXXV. The Chemical Constituents of the Heartwood of Maackia amurensis var. buergeri.
• 13. lentinanの抗腫瘍性と抗補体性(第9回補体シンポジウム)
• Studies on the Saponins of the Root of Platycodon grandiflorum A. DE CANDOLLE. I. Isolation and the Structure of Platycodin-D
• Chemical Studies on the Oriental Plant Drugs. XX. The Constituents of Cassia tora L. (1). The Structure of Torachrysone
• 2 菌類代謝産物の化学 : Rugulosin,Luteoskyrin,Rubroskyrinおよび関連化合物の研究
• The Chemical Studies on Oriental Plant Drugs. XVIII. The Constituents of Bupleurum spp. (3). Saikogenins E and G
• Studies on the Constituents of Japanese and Chinese Crude Drugs. IX. Paeoniflorin, A Glucoside of Chinese Paeony Root. (2).
• Constituents of Chinese Crude Drug "Wujiapi." I. Studies on the Aglycones of Steroidal Glycosides of Pei-wujiapi. (1)
• Studies on the Chemical Constituents of Chinese Drug "Wujiapi"
• Decomposition of Usnic Acid. VI. Studies on the Ozonolytic Products of O, O-Diacetylusnic Acid.
• Studies on the Structure of Itaconitin. IV. The Reactions of Itaconitin and Anhydroitaconitin
• 18 Aspergillus itaconicusの色素,Itaconitin,の構造について
• A Polysaccharide of the Lichen, Stereocaulon Japonicum
• A New Isoflavone and the Corresponding Isoflavanone of Licorice Root
• A New Isoflavone from Licorice Root
• A New 3-Arylcoumarin from Licorice Root
• Peptides in Higher Plants. II. The Crystal Structure of Tri-N-methylfrangulanine Methiodide
• Metabolic Products of Fungi. XXIII. On Ustilaginoidins. (3). The Structures of Ustilaginoidins B and C.
• Metabolic Products of Fungi. XX. The Biosynthesis of Rugulosin.
• Metabolic Products of Fungi. XVII. The Structure of Flavoskyrin.
• 4 地衣Usnea bayleyi黄色色素 : Eumitrinの構造について
• The Correlation between the Antitumor Activities and Chemical Structures of Thiocyanato Derivatives of Purines and Their Ribonucleosides
• The Chemical Studies on Oriental Plant Drugs. XV. On the Constituents of Bupleurum Spp. (2). The Structure of Saikogenin A, a Sapogenin of Bupleurum falcatum L.
• Biosynthesis of Lichen Substances. II. Participation of C_1-Unit to the Formation of β-Orcinol Type Lichen Depside
• Biosynthesis of Lichen Depsides, Lecanoric Acid and Atranorin
• Studies on Antitumor Activity of Some Fractions from Basidiomyces. I. An Antitumor Acidic Polysaccharide Fraction of P. ostreatus (Fr.) QUEL
• Metabolic Products of Fungi. XVIII. On the Structure of Lumiluteoskyrin.
• Metabolic Products of Fungi. XVI. The Structures of Rubroskyrin and Luteoskyrin.
• Flavonols of Licorice Root
• New Isoflavan and Flavanone from Licorice Root
• Chemical Studies on the Oriental Plant Drugs. XXXVI. Structure of Licoricone, a New Isoflavone from Licorice Root
• Chemical Studies on the Oriental Plant Drugs. XXII. Some New Constituents of Licorice Root. (2) Glycyrol, 5-O-Methylglycyrol and Isoglycyrol
• The Chemical Studies on the Oriental Plant Drugs. XIX. Some New Constituents of Licorice Root. (1). The Structure of Licoricidin
• Phytochemical Investigation on Cultivation of Medicinal Plants. XV. The Biogenesis of Ephedrine in Ephedra. (5).
• On Methyl-1-phenylnaphthalenes. II. The Gas Chromatography of Methyl-1-phenylnaphthalenes.
• Antitumor Activity of Shikonin and Its Derivatives
• ミシマサイコ(Bupleurum falcatum L.)の栽培試験
• 44 Penicillium属Anthraquinonoidsの生合成
• Polysaccharides of Lichens and Fungi. V. Antitumour Active Polysaccharides of Lichens of Evernia, Acroscyphus and Alectoria spp.
• Polysaccharides of Lichens and Fungi. IV. Antitumour Active O-Acetylated Pustulan-Type Glucans from the Lichens of Umbilicaria Species
• Polysaccharides in Lichens and Fungi. III. Further Investigation on the Structures and the Antitumor Activity of the Polysaccharides from Gyrophora esculenta MIYOSHI and Lasallia papulosa LLANO
• Studies on the Chemical Structures of the New Glucans isolated from Gyrophora esculenta MIYOSHI and Lasallia papulosa (ACH.) LLANO and Their Inhibiting Effect on Implanted Sarcoma 180 in Mice
• Metabolic Products of Fungi. XV. Pachymic Acid, a Constituent of"Bukuryo"(Fu Ling茯苓), a Sclerotium of Poria cocos (SCHW.) WOLF.
• Peptides in Higher Plants. I. The Conformation of Frangulanine
• Metabolic Products of Fungi. XIX. Isolation of Rugulosin from Penicillium brunneum UDAGAWA.
• Synthetic Nucleosides and Nucleotides. XI. : Facile Synthesis and Antitumor Activities of Various 5-Fluoropyrimidine Nucleosides
• Immunosuppressive activity of heat-stable toxohormone fraction from cell-free fluid of ascites sarcoma-180(Note)
• 6.RhizopusのRiboflavin cyclic monophosphateのCytocidal Action(THE JOURNAL OF VITAMINOLOGY : 掲載論文要旨)
• 26-I-22 Riboflavin cyclic phosphateの生理活性に関する研究(研究発表 日本ビタミン学会 : 第24回大会研究)
• A New α-Glucan from the Lichen Parmelia caperata (L.) ACH.
• Polysaccharides in Lichens and Fungi. I. Antitumour Active Polysaccharides of Gyrophora esculenta MIYOSHI and Lasallia papulosa (ACH.) LANO
• Relationship between Antitumor Effect of Polysaccharides and Biogenic Amines in Tumor Tissues
• Antitumor activity of polysaccharides from Serratia marcescens(Note)
• Antitumor Effect of Polysaccharides and Its Relationship to Biogenetic Amines in Tumor Tissues under Vitamin B_6 Deficient Feeding
• The Occurrence of an Isoflavene and the Corresponding Isoflavone in Licorice Root
• On Methylphenylnaphthalenes. I. Syntheses of Methylphenylnaphthalenes.
• Metabolic Products of Fungi. XXV. Synthesis of Rubrofusarin and Its Derivatives.
• Synthesis of Rubrofusarin Dimethyl Ether
• Studies on the Constituents of Japanese and Chinese Crude Drugs. VII. On the Constituents of the Roots of Sophora subprostrata CHUN et T. CHEN, (2), and Sophora japonica L. (1).
• Formation of Lichen Substances by Mycobionts of Lichens. Isolation of (+) Usnic Acid and Salazinic Acid from Mycobionts of Ramalina spp.
• Metabolic Products of Fungi. XXII. On Ustilaginoidins. (2). The Structure of Ustilaginoidin A.
• Metabolic Products of Fungi. XXI. On Ustilaginoidins. (1). The Reactions of Ustilaginoidin A.

もっと見る 閉じる

スポンサーリンク