New Route to 1-(5-Imidazolyl)ribofuranoid Glycals from Ribofuranosyl Chloride and 5-Lithio-imidazole

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概要

• 論文の詳細を見る

• Reaction of ribofuranosyl chlorides with 2 eq of 5-lithio-imidazole afforded 1-(5-imidazolyl)ribofuranoid glycals in good yields. Hydrolysis of the glycal (3) with hydrochloric acid led to 4-(5-hydroxymethylfuran-2-yl)imidazole (7), which contains both hydrophilic and hydrophobic aromatic heterocycles.

• 公益社団法人日本薬学会の論文
• 1995-01-15

著者

• 春沢 信哉

  Osaka University of Pharmaceutical Sciences

• 米田 龍司

  Osaka University of Pharmaceutical Sciences

• 栗原 拓史

  大阪薬科大学

• 米田 龍司

  Agroscience Research Laboratories Sankyo Co. Ltd.

• 村井 良彦

  Osaka University Of Pharmaceutical Sciences

• 栗原 拓史

  Osaka College Of Pharmacy

• 川端 雅世

  Osaka University of Pharmaceutical Sciences

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