Allylic Rearrangement of Cyanophosphates. III. : Reaction of Acyclic Enone Cyanophosphates
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概要
- 論文の詳細を見る
Boron trifluoride-catalyzed allylic rearrangement of α, β-unsaturated ketone cyanophosphates (2,6 and 12) gave (Z)-4-diethylphosphonooxy-2-butenenitriles (3,8 and 13), while α, β-unsaturated aldehyde cyanophosphates (17a-c) afforded (E)-4-diethylphosphonooxy-2-butenenitriles (18a-c) stereoselectively. The stereo- and regioselective reaction of 2 with several kinds of aromatics in the presence of boron trifluoride etherate afforded (Z)-4-aryl-2-methyl-2-butenenitriles (20) via the SN2' reaction. On the other hand, treatment of 2 with 1-subsituted indoles in the presence of boron trifluoride etherate gave 1-amino-2-methylcarbazole derivatives (23a-c).
- 公益社団法人日本薬学会の論文
- 1986-11-25
著者
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春沢 信哉
Osaka University of Pharmaceutical Sciences
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米田 龍司
Osaka University of Pharmaceutical Sciences
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三木 益生
Osaka College of Pharmacy
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栗原 拓史
Osaka College Of Pharmacy
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山東 一孔
Osaka University Of Pharmaceutical Sciences
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三木 益生
Osaka University Of Pharmaceutical Sciences
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