[3,3]Sigmatropic Ring Expansion of Cyclic Thionocarbonates. IV. Relatioship between Ring Size of Cyclic Thionocarbonates and Geometry of Created Double Bond in Medium- and Large-Membered Thiolcarbonates
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概要
- 論文の詳細を見る
Medium- and large-membered cyclic thiolcarbonates containing an (E)- or (Z)-double bond were synthesized by two methods using [3,3]sigmatropic ring expansion of cyclic thionocarbonates. The [3,3]sigmatropic ring expansion proceeds exclusively via the transition state bearing the chain tethered in a cis relationship when the cyclic thionocarbonates are 8-membered or smaller. Importantly, the ring size of the cyclic thionocarbonate determines the double bond geometry of the thiolcarbonate.Conversion of the cyclic thiolcarbonates into (E)- or (Z)-allylic sulfides is also described.
- 公益社団法人日本薬学会の論文
- 1991-07-25
著者
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春沢 信哉
Osaka University of Pharmaceutical Sciences
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米田 龍司
Osaka University of Pharmaceutical Sciences
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栗原 拓史
大阪薬科大学
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大崎 浩孝
Osaka University of Pharmaceutical Sciences
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藤井 晴美
Osaka Uniersity Of Pharmaceutical Sciences
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米田 龍司
Agroscience Research Laboratories Sankyo Co. Ltd.
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栗原 拓史
Osaka College Of Pharmacy
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大嵜 浩考
Osaka Uniersity of Pharmaceutical Sciences
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黒川 登志子
Osaka Uniersity of Pharmaceutical Sciences
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