Synthetic Study of (9S)-9-Dihydroerythronolide A via Witting-Horner Coupling of C1-C6 and C7-C15 Segments
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概要
- 論文の詳細を見る
As part of a study directed at the total synthesis of (9S)-9-dihydroerythronolide A, Wittig-Horner coupling was carried out between the C7-C15 segment, (2S, 3R, 4S, 5R, 6R, 7R)-3,5-isopropylidenedioxy-7-(4-methoxybenzyloxy)-6-methoxymethoxy-2,4,6-trimethylnonanal synthesized from the C9-C15 triol, and the C1-C6 segment, diethyl (2RS, 4S, 5R, 6R)-6-tert-butyldimethylsilyloxy-4-(3,4-dimethoxybenzyloxy)-2-oxo-1,3,5-trimethylhexylphosphonate synthesized from the C1-C5 diol, to obtain the C1-C15 enone, although the yield was poor.
- 社団法人日本薬学会の論文
- 1989-05-25
著者
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及川 裕二
Faculty Of Pharmaceutical Sciences Hokkaido University
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米光 宰
岡山理大理
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米光 宰
Faculty of Pharmaceutical Sciences, Hokkaido University
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及川 裕二
北大薬
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米光 宰
Faculty Of Pharmaceutical Sciences Hokkaido University
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西 孝夫
Third Institute of New Drug Research Otsuka Pharmaceutical Co., Ltd.,
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西 孝夫
Third Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
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利根 斉
Faculty of Pharmaceutical Sciences, Hokkaido University
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西 孝夫
Faculty of Pharmaceutical Sciences, Hokkaido University
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彦田 匡毅
Faculty of Pharmaceutical Sciences, Hokkaido University
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彦田 匡毅
北大薬
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Nishi Takao
Third Institute Of New Drug Research Otsuka Pharmaceutical Co. Ltd.
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利根 斉
Faculty Of Pharmaceutical Sciences Hokkaido University
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