Studies on the Metabolic Products of Aspergillus terreus. II. Structure and Biosynthesis of the Metabolites of the Strain ATCC12238
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概要
- 論文の詳細を見る
New compounds, 6-hydroxytoluquinol-hydrate (3,4) (VI), terremutin-hydrate (VII), and 4-chloro-3,6-dihydroxytoluquinone (II) were isolated from Aspergillus terreus ATCC 12238 together with terreic acid, terremutin, 3,6-dihydroxytoluquinone, and terrein. The metabolic relationships among the metabolites were studied by administration experiments using ^<14>C-compounds and the metabolic scheme was proposed. The metabolic pattern of"epoxy compounds (terreic acid and terremutin)→quinone (3,6-dihydroxytoluquinone) or its quinol→hydroaromatic compound (VI)"was essentially the same as observed in Aspergillus fumigatus DH 413 and IFO 4399.
- 社団法人日本薬学会の論文
- 1977-06-25
著者
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桐山 典城
Faculty of Pharmaceutical Sciences, Hokuriku University
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山本 譲
Faculty of Pharmaceutical Sciences, Kanazawa Unversity
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山本 譲
Faculty Of Pharmaceutical Sciences Kanazawa University
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樋口 善博
Faculty of Pharmaceutical Sciences, Kanazawa University
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樋口 善博
Faculty Of Pharmaceutical Sciences Kanazawa University
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桐山 典城
Faculty Of Pharmaceutical Sciences Kanazawa University
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桐山 典城
Faculty Of Pharmaceutical Sciences Hokuriku University
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