Studies on the Metaboic Products of a Strain of Aspergillus fumigatus (DH 413). I. Isolation and Chemical Structures of Metabolites
スポンサーリンク
概要
- 論文の詳細を見る
Several fungal pigments were isolated by cultivation of a strain of Aspergillus fumigatus which was isolated from the dust of asthmatic patients' rooms. Spinulosin, fumigatin and its quinol (m.p. 107.5〜109°) were determined, though the melting point of the quinol was rather much different from the literature (99〜101°). The chemical structure of a new metabolite, m.p. 74°(II) was determined as 2-methyl-5-methoxy-6-hydroxy-p-benzoquinone 2,3-epoxide. Another compound, m.p.182°(IV) was found to have a closely related structure to II. Compound, m.p.204° had p-quinone moiety in the structure, but not the C_8 compound different from all other metabolites.
- 社団法人日本薬学会の論文
- 1965-08-25
著者
-
山本 譲
Faculty of Pharmaceutical Sciences, Kanazawa Unversity
-
新田 啓一
Faculty of Pharmaceutical Sciences, Kanazawa University
-
山本 譲
Faculty Of Pharmaceutical Sciences Kanazawa University
-
山本 譲
Faculty Of Pharmaceutical Sciences Kanazawa Unversity
-
丹後 紀美子
Faculty of Pharmacy, Kanazawa University
-
斎藤 妙子
Faculty of Pharmacy, Kanazawa University
-
土室 美紀子
Faculty of Pharmacy, Kanazawa University
-
斎藤 妙子
Faculty Of Pharmacy Kanazawa University
-
新田 啓一
Faculty Of Pharmaceutical Sciences Kanazawa University
-
丹後 紀美子
Faculty Of Pharmacy Kanazawa University
-
土室 美紀子
Faculty Of Pharmacy Kanazawa University
関連論文
- Amino Acids and Peptides. XXV. Preparation of Fibronectin-Related Peptide Poly(ethylene glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
- Amino Acids and Peptides. XXI. Laminin-Related Peptide Analogs Including Poly(Ethylene Glycol) Hybrids and Their Inhibitory Effect on Experimental Metastasis
- PREPARATION OF [ARG-GLY-ASP]-[AMINO-POLY(ETHYLENE GLYCOL)] HYBRIDS AND THEIR INHIBITORY EFFECT ON EXPERIMENTAL METASTASIS
- Reaction of Methyl 4,5-Epoxy-(2E)-pentenoate with Arenes. II. Application to the Synthesis of (±)-Curcudiol, (±)-Curcuphenol, (±)-Curcuhydroquinone, and (±)-Curcuquinone
- Reaction of Methyl 4,5-Epoxy-(2E)-pentenoate with Arenes. I. A Facile Synthesis of 4-Aryl-5-hydroxy-(2E)-pentenoate Derivatives
- Metabolic Products of Aspergillus terreus. X. : Biosynthesis of Asterriquinones
- Metabolites of Penicillium italicum WEHMER : Isolation and Structures of New Metabolites Including Naturally Occurring 4-Ylidene-acyltetronic Acids, Italicinic Acid and Italicic Acid
- Structures of Fructigenines A and B, New Alkaloids Isolated from Penicillium fructigenum TAKEUCHI
- CASTANEIOLIDE, ABSCISIC ACID AND MONORDEN, PHYTOTOXIC COMPOUNDS ISOLATED FROM FUNGI (MACROPHOMA CASTANEICOLA AND DIDYMOSPORIUM RADICICOLA) CAUSE "BLACK ROOT ROT DISEASE" IN CHESTNUT TREES
- Asperinines A and B, Dimeric Tetrahydroanthracene Derivatives from Aspergillus ruber
- Metabolic Products of Aspregillus terreus. VI. Metabolites of the Strain IFO 8835. (3). The Isolation and Chemical Structures of Colorless Metabolites
- Metabolic Products of Aspergillus terreus. V. Demethylation of Asterriquinones
- Studies on Metabolites of Macrophoma commelinae. IV. : Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids
- Studies on Metabolites of Macrophoma commelinae. III. : Isolation of New Metabolites and Biosynthesis of Macommelin Group
- NOVEL BIOTRANSFORMATION OF A 2-PYRONE TO A SUBSTITUTED BENZOIC ACID
- ISOLATION AND STRUCTURE OF MACOMMELINS, NOVEL METABOLITES OF MACROPHOMA COMMELINAE
- Antitumor Activity of Asterriquinones from Aspergillus Fungi. IV. An Attempt to modify the Structure of Asterriquinones to increase the Activity
- Metabolic Products of Aspergillus terreus. VII. Astechrome : an Iron-containing Metabolite of the Strain IFO 6123
- Metabolic Products of Aspergillus terreus. IV. Metabolites of the Strain IFO 8835. (2). The Isolation and Chemical Structure of Indolyl Benzoquinone Pigments
- ο-Chloro-α-(tert-butylaminomethyl)-benzyl Alcohol Hydrochloride(C-78)の生体内運命(第2報^)ラットにおける代謝物
- 2-Thio-6-methyluracilのラットにおける代謝について
- Amino Acids and Peptides. XIX. Preparation of Enkephalin-Poly(ethylene glycol) Hybrid and Evaluation of Its Analgesic Activity
- オクテット
- Studies on the Metabolic Products of Aspergillus terreus. II. Structure and Biosynthesis of the Metabolites of the Strain ATCC12238
- ο-Chloro-α-(tert-butylaminomethyl)-benzyl Alcohol Hydrochloride(C-78)の生体内運命(第3報^)ラット肝臓におけるin Vitro代謝
- Metabolic Products of Aspergillus terreus. IX. Biosynthesis of Butyrolactone Derivatives isolated from Strains IFO 8835 and 4100
- Stereochemical Correlation of Di- and Trihydroxy-β-diketone Fungal Metabolites, (-)-Terredionol and Terremutin Hydrate, with Sugar Alcohols : The Absolute Configuration of (-)-Terredionol
- Studies on the Metabolic Products of a Strain of Aspergillus fumigatus DH 413. VI. Metabolic Position of 3,4-Dihydroxytoluquinone and Fumigatin Chlorohydrin in Fumigatin Biosynthesis
- Studies on the Metabolic Products of a Strain of Aspergillus fumigatus DH 413. V. A New Metabolite produced by Ethionine Inhibition
- Studies on the Metabolic Products of a Strain of Aspergillus fumigatus (DH 413). IV. Biosynthesis of Toluquinones and Chemical Structures of New Metabolites
- Studies on the Metabolic Products of Oospora astringenes. VIII. Isolation, Chemical Structure, and Biosynthesis of Oospolide
- Studies on the Metabolic Products of a Strain of Aspergillus fumigatus (DH 413).III.Biosynthesis of Toluquinones
- Studies on the Metabolic Products of Oospora astringenes. VII. Biogenesis of Oospolactone and Oosponol
- Studies on the Metabolic Products of a Strain of Aspergillus fumigatus (DH 413). II. Biosynthsis of Metabolites
- Studies on the Metaboic Products of a Strain of Aspergillus fumigatus (DH 413). I. Isolation and Chemical Structures of Metabolites
- In Vivo Evaluation of Carborane Gadolinium-DTPA Complex as an MR Imaging Boron Carrier
- Trichothecium roseum LINKの代謝産物の研究Rosein IIIの構造
- Synthesis and Biological Activity of Opioid Peptides Replaced Phenylalanine at Position 3 or 4 by 2, 6-Dimethylphenylalanine
- Biological Properties of Opioid Peptides Replacing Tyr at Position 1 by 2,6-Dimethyl-Tyr
- Racemization Kinetics of Meluadrine Tartrate in Aqueous Solution
- Characterization of the CYP2C8 Active Site by Homology Modeling
- Characterization of the CYP3A4 Active Site by Homology Modeling
- Studies on Quinolone Antibacterials. V. Synthesis and Antibacterial Activity of Chiral 5-Amino-7-(4-substituted-3-amino-1-pyrrolidinyl)-6-fluoro-1,4-dihydro-8-methyl-4-oxoquinoline-3-carboxylic Acids and Derivatives
- Studies on Quinolone Antibacterials. IV. Structure-Activity Relationships of Antibacterial Activity and Side Effects for 5- or 8-Substituted and 5,8-Disubstituted-7-(3-amino-1-pyrrolidinyl)-1-cycloporpyl-1,4-dihydro-4-oxoquinoline-3-carboxylic Acids
- Conformation of 2-Aminomethylpyrrolidine and 2-Aminomethylpiperidine in Ternary Platinum (II) Complexes : Regulation of Conformation of the Diamine by the Coexisting Ligand
- Synthesis of Optically Active α-(p-Chlorophenyl)pyridylmethanols with Plant Cell Cultures
- Tetrabutylammonium Fluoride Promoted Regiospecific Reactions of Trimethylsilyl-o-Carborane with Aldehydes
- Effect of Inhibitor or Immobilization on Reduction of Benzoylpyridines by Baker's Yeast
- A New Water-soluble p-Boronophenylalanine Derivative for Neutron Capture Therapy
- Studies on the Metabolic Products of Aspergillus terreus. III. Metabolites of the Strain IFO 8835. (1)
- Studies on the Metabolic Products of Aspergillus terreus. I. Metabolites of the Strain IFO 6123
- Studies on the Metabolic Products of Aspergillus fumigatus (J-4). Chemical Structure of Metabolic Products