Improved Preparation of Sulfur Substituted 3-Vinylpyrrole and Its Application to the Syntheses of Chuangxinmycin Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
Sulfur substituted 3-vinylpyrrole 10 was prepared from 3-thio-acetylpyrrole 9 by alkylation with alkyl halide in the presence of propylene oxide. Functionalized 4-alkylthioindoles were made by Diels-Alder reaction of the 3-vinylpyrrole 10 with dienophiles. Chuangxinmycin analogues were synthesized by using some of the functionalized 4-alkylthioindoles as key intermediates.
- 2001-09-01
著者
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吉田 隆志
Department Of Pharmacognosy College Of Pharmaceutical Sciences Matsuyama University
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Yoshida T
Department Of Microbiology Hiroshima University School Of Medicine
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吉田 隆志
College Of Pharmaceutical Sciences Matsuyama University
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Yoshida Takuji
Showa College Of Pharmaceutical Sciences
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MURASE Masayuki
Showa Pharmaceutical University
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KOTANI Eiichi
Showa Pharmaceutical University
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Kotani E
Showa Pharmaceutical University
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Kotani Eiichi
Showa College Of Pharmaceutical Sciences
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Murase M
Showa Pharmaceutical University
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Murase Masayuki
Showa College Of Pharmaceutical Sciences
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ITO Ai
Showa Pharmaceutical University
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IBUSUKI Kei
Showa Pharmaceutical University
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Ito A
Chiba Univ. Chiba Jpn
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Murase M
Showa College Of Pharmaceutical Sciences
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