3-Benzamido, Ureido and Thioureidoimidazo[1, 2-a]pyridine Derivatives as Potential Antiviral Agents
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概要
- 論文の詳細を見る
This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenylthioureido derivatives in the imidazo[1, 2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluated against a large number of viruses. The 3-phenylthioureido derivative 7 showed moderate activity against human cytomegalovirus(HCMV) in vitro. The crystallographic data for 8 are also reported and explain the absence of activity against human immunodeficiency virus(HIV).
- 社団法人日本薬学会の論文
- 2001-12-01
著者
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De Clercq
Rega Inst. For Medical Res. Katholieke Universiteit Leuven
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SNOECK Robert
Rega Institute for Medical Research, Katholieke Universiteit Leuven
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ANDREI Graciela
Rega Institute for Medical Research, Katholieke Universiteit Leuven
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BALZARINI Jan
Rega Institute for Medical Research, Katholieke Universiteit Leuven
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PANNECOUQUE Christophe
Rega Institute for Medical Research, Katholieke Universiteit Leuven
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CHAOUNI-BENABDALLAH Aziz
E.A.Groupe de Recherche en Chimie Heterocyclique et Therapeutique, Laboratoire de Chimie Therapeutiq
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GALTIER Christophe
E.A.Groupe de Recherche en Chimie Heterocyclique et Therapeutique, Laboratoire de Chimie Therapeutiq
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ALLOUCHI Hassan
Laboratoire de Chimie Physique, Faculte de Pharmacie
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KHERBECHE Abdelak
Laboratoire de Catalyse et Environnement, Universite Sidi Mohamed Ben Abdellah, Ecole Superieure de
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CHAVIGNON Olivier
Laboratoire de Chimie Organique, Faculte de Pharmacie
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TEULADE Jean-Claude
Laboratoire de Chimie Organique, Faculte de Pharmacie
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WITVROUW Myriam
Rega Institute for Medical Research, Katholieke Universiteit Leuven
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FAUVELLE Florence
Centre de Recherche du Service de Sante des Armees
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ENGUEHARD Cecile
BCM
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GUEIFFIER Alain
E.A.Groupe de Recherche en Chimie Heterocyclique et Therapeutique, Laboratoire de Chimie Therapeutiq
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Blanco Jose
Departamento De Farmacologia Facultade De Farmacia Universidade De Santiago De Compostela
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Snoeck Robert
Rega Instituut Katholieke Universiteit Leuven
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Snoeck Robert
Rega Institute For Medical Research Katholieke Universiteit Leuven
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Balzarini J
Rega Inst. For Medical Res.
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CHAVIGNON Olivier
Faculte de Pharmacie UMR-INSERM 484
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GUEIFFIER Alain
Laboratoire de Chimie Therapeutique SPOT EA 3857, Faculte de Pharmacie
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Andrei Graciela
Rega Instituut Katholieke Universiteit Leuven
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Andrei Graciela
Rega Institute For Medical Research Katholieke Universiteit Leuven
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Pannecouque Christophe
Rega Instituut Katholieke Universiteit Leuven
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Pannecouque C
Katholieke Univ. Leuven Leuven Bel
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Balzarini Jan
Rega Inst. For Medical Res.
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Balzarini J
Rega Institute For Medical Research Katholieke Universiteit Leuven
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Chavignon O
Ufr De Pharmacie Clermont‐ferrand Fra
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Teulade J‐c
Laboratoire De Chimie Organique Ea 3660 Faculte De Pharmacie
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Pannecouque Christophe
Rega Inst. For Medical Res. Katholieke Universiteit Leuven
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Allouchi Hassan
Laboratoire De Chimie Physique Faculte De Pharmacie
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Teulade Jean-claude
Laboratoire De Chimie Organique Ea 3660 Faculte De Pharmacie
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Chavignon Olivier
Laboratoire De Chimie Organique Pharmaceutique Groupe De Recherche En Pharmacochimie Ufr De Pharmaci
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Teulade Jean-claude
Laboratoire De Chimie Organique Faculte De Pharmacie
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Witvrouw Myriam
Rega Instituut Katholieke Universiteit Leuven
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Gueiffier A
E.a.groupe De Recherche En Chimie Heterocyclique Et Therapeutique Laboratoire De Chimie Therapeutiqu
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Galtier Christophe
E.a.groupe De Recherche En Chimie Heterocyclique Et Therapeutique Laboratoire De Chimie Therapeutiqu
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Chaouni-benabdallah Aziz
E.a.groupe De Recherche En Chimie Heterocyclique Et Therapeutique Laboratoire De Chimie Therapeutiqu
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Kherbeche Abdelak
Laboratoire De Catalyse Et Environnement Universite Sidi Mohamed Ben Abdellah Ecole Superieure De Te
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Allouchi Hassa
Laboratoire de Chimie Physique, Faculte de Pharmacie
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