ULTRASTRUCTURAL AND CYTOCHEMICAL OBSERVATIONS ON HETEROPHAGY AND AUTOPHAGY OF MACROPHAGE IN MOUSE THYMUS
スポンサーリンク
概要
- 論文の詳細を見る
Ultrastructural changes of macrophage in mouse thymus during exogenous (heterophagy) and endogenous material (autophagy) digestive process were investigated with the cytochemical demonstration of acid phosphatase (AcPase) activity. During the phagocytosis of macrophage, an apparent periodic change could be observed in the lysosomal system. According to this periodic change, we proposed a new concept of phagocytosis period. This period could be divided into a heterophagocytosis stage and an autophagocytosis stage. The main feature of the heterophagocytosis stage was that the activity of phagocytosis increased, a large number of irregularly shaped heterophagolysosomes (HPL) were formed, then many small lysosomes were formed by budding and pinching-off from the HPL. In the autophagocytosis stage, a lot of small lysosomes were wrapped by the irregular-shaped HPL. It was indicated that in the autophagocytosis stage the autophagy of macrophage was a phenomenon of self-phagocytosis of HPL.
- 日本組織細胞化学会の論文
著者
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Ogawa Kazuo
Department of Cardiology, Jikei University
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Piao Ying
Department Of Computer Science And Department Of Central Laboratory The First Medical College Of Pla
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Piao Ying
Department Of Histology The First Medical College Of Pla Guangzhou People's Republic Of China
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Piao Ying
Department Of Anatomy Faculty Of Medicine Kyoto University
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Ogawa Kazuo
Department Of Anatomy Faculty Of Medicine Kyoto University
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Ogawa Kazuo
Department Of Anatomy Kyoto University Faculty Of Medicine
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Ogawa Kazuo
Department Of Anatany Faculty Of Medicine Kyoto University
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