A Composite of Hydroxyapatite with Electrospun Biodegradable Nanofibers as a Tissue Engineering Material(CELL AND TISSUE ENGINEERING, <Special Issue>Advances in Biomedical Science and Engineering)

スポンサーリンク

概要

• 論文の詳細を見る

• Biodegradable and biocompatible poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), a copolymer of microbial polyester, was fabricated as a nanofibrous film by electrospinning and composited with hydroxyapatite (HAp) by soaking in simulated body fluid. Compared with a PHBV cast (flat) film, the electrospun PHBV nanofibrous film was hydrophobic. However, after HAp deposition, both of the surfaces were extremely hydrophilic. The degradation rate of HAp/PHBV nanofibrous films in the presence of polyhydroxybutyrate depolymerase was very fast. Nanofiber formation increased the specific surface area and HAp enhanced the invasion of enzyme into the film by increasing surface hydrophilicity. The surface of the nanofibrous film showed enhanced cell adhesion over that of the flat film, although cell adhesion was not significantly affected by the combination with HAp.

• 社団法人日本生物工学会の論文
• 2005-07-25

著者

• KAMITAKAHARA Masanobu

  Graduate School of Environmental Studies, Tohoku University

• OHTSUKI Chikara

  Graduate school of Engineering, Nagoya University

• Kamitakahara Masanobu

  Graduate School Of Environmental Studies Tohoku University

• Kamitakahara Masanobu

  Graduate School Of Environmental Studies Tohoku Univ.

• Ohtsuki Chikara

  Department Of Crystalline Materials Science Graduate School Of Engineering Nagoya University

• Ohtsuki Chikara

  Graduate School Of Engineering Nagoya Univ.

• Ohtsuki C

  Department Of Crystalline Materials Science Graduate School Of Engineering Nagoya University

• Ohtsuki Chikara

  Dep. Of Crystalline Materials Sci. Graduate School Engineering Nagoya Univ.

• Ohtsuki Chikara

  奈良先端科学技術大学院大学 物質創成科学研究科

• KWON Oh

  Department of Chemical Engineering, Hongik University

• Ohtsuki Chikara

  Graduate School Of Engineering Nagoya University

• Kwon Oh

  Department Of Anatomy College Of Medicine Chungnam National University

• TANIHARA Masao

  Graduate School of Materials Science, Nara Institute of Science and Technology

• ITO Yoshihiro

  Kanagawa Academy of Science and Technology

• Hasuda Hirokazu

  Kanagawa Academy of Science and Technology

• Kang Inn

  Department of Polymer Science, Kyungpook National University

• Kang Inn

  Department Of Polymer Science Kyungpook National University

• Tanihara Masao

  Graduate School Of Material Science Nara Institute Of Science And Technology

• Kwon Oh

  Department Of Polymer Science And Engineering Kumoh National Institute Of Technology

• Ito Yoshihiro

  Nano Medical Engineering Laboratory Riken Advanced Science Institute

• Hasuda Hirokazu

  Kanagawa Acad. Of Sci. And Technol.

• Tanaka Mamoru

  Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie

• Tanihara Masao

  Department Of Gastroenterology And Metabolism Nagoya City University Graduate School Of Medical Scie

• Kwon Oh

  Department Of Aerospace Engineering Kaist

関連論文

• Synthesis of Bioactive HEMA-MPS-CaCl2 Hybrid Gels: Effects of Catalysts in the Sol-Gel Processing on Mechanical Properties and in vitro Hydroxyapatite Formation in a Simulated Body Fluid
• Protein adsorption on needle-shaped hydroxyapatite prepared by hydrothermal treatment of mixture composed of CaHPO_4・2H_2O and β-Ca_3(PO_4)_2
• Hydroxyapatite-forming capability and mechanical properties of organic-inorganic hybrids and α-tricalcium phosphate porous bodies
• Evaluation of apatite-forming ability and mechanical property of pectin hydrogels( Ceramics for Biomedical Applications in Asian Countries)
• Combination chemotherapy with cisplatin and gemcitabine in malignant peritoneal mesothelioma
• Effects of Indium-Tin-Oxide Surface Treatment on Organic Light-Emitting Diodes
• Optical Microscopy and Scanning Electron Microscopy on the Surface of Rice Callus after Treatment with Cell Wall Degrading Enzymes
• Clinical efficacies of topical agents for the treatment of seborrheic dermatitis of the scalp : A comparative study
• The Additive Effects of Minoxidil and Retinol on Human Hair Growth in Vitro(Molecular and Cell Biology)
• Non-invasive evaluation of hair interior morphology by X-ray microscope
• Androgenetic alopecia in adolescents : A report of 43 cases
• Perifollicular Fibrosis : Pathogenetic Role in Androgenetic Alopecia(Biochemistry)
• Bleaching Phototrichogram : An Improved Method for Hair Growth Assessment
• Expression of androgen receptor, estrogen receptor α and β in the dermal papilla of human hair follicles in vivo
• Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle
• Behavior of β-tricalcium phosphate granules composed of rod-shaped particles in the rat tibia
• Development of a Bone-Repairing Material Through Hybridization of Biodegradable Polymer with Bone-like Apatite(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
• Predicting Aerodynamic Rotor-Fuselage Interactions by Using Unstructured Meshes
• Effects of 20-Hydroxyecdysone and Serotonin on Neurite Growth and Survival Rate of Antennal Lobe Neurons in Pupal Stage of the Silk Moth Bombyx mori in vitro(Neurobiology)
• Structure-Photodynamic Effect Relationships of 24 Glycoconjugated Photosensitizers in HeLa Cells(Medicinal Chemistry)
• Microstructure and Bioresorbable Properties of α-TCP Ceramic Porous Body Fabricated by Direct Casting Method
• Hydrothermal synthesis and characterization of hydroxyapatite from octacalcium phosphate
• Hydrothermal synthesis of hydroxyapatite from octacalcium phosphate : effect of hydrothermal temperature(Aqueous Solution Science for Ceramic Processing II)
• Evaluation of photocatalytic activity of anatase/hydroxyapatite composite granules for environmental purification
• Hydrothermal synthesis of magnetite/hydroxyapatite composite material for hyperthermia therapy for bone cancer
• Hepatocyte Growth Factor Fusion Protein Having Collagen-Binding Activity (CBD-HGF) Accelerates Re-endothelialization and Intimal Hyperplasia in Balloon-injured Rat Carotid Artery
• Formation of needle-like hydroxyapatite by hydrothermal treatment of CaHPO_4・2H_2O combined with β-Ca_3(PO_4)_2
• Induced deposition of bone-like hydroxyapatite on thermally oxidized titanium substrates using a spatial gap in a solution that mimics a body fluid
• Hybridization of silver nanoparticles on hydroxyapatite in an aqueous solution(Aqueous Solution Science for Ceramic Processing II)
• Synthesis of octacalcium phosphate intercalated with dicarboxylate ions from calcium carbonate and phosphoric acid
• Surface Topography Designed to Provide Osteoconductivity to Titanium after Thermal Oxidation
• Formation of hydroxyapatite on ceramics consisting of tricalcium phosphate in a simulated body fluid( Ceramics for Biomedical Applications in Asian Countries)
• Synthesis of ceramics in MO_-SiO_2 systems through sol-gel processing under coexistence of polyethylene glycol and in vitro evaluation of their bioactivity( Ceramics for Biomedical Applications in Asian Countries)
• Preparation of hydroxyapatite porous ceramics with different porous structures using a hydrothermal treatment with different aqueous solutions( Ceramics for Biomedical Applications in Asian Countries)
• Effect of Silane-Coupling Treatment on Thermal Decomposition of Octacalcium Phosphate
• A Composite of Hydroxyapatite with Electrospun Biodegradable Nanofibers as a Tissue Engineering Material(CELL AND TISSUE ENGINEERING, Advances in Biomedical Science and Engineering)
• Control of the Microstructure of Porous Tricalcium Phosphate: Effects of addition of Mg, Zn and Fe (特集 バイオ機能材料・バイオインスパイアード材料)
• 11-O-29 Formation of Octacalcium Phosphate from α-TCP Porous Body
• 11-O-18 Graded Structure on Bioactive Metal Induced by Chemical Surface Modification
• 11-I-01 Bioactivity of MgO-CaO-SiO_2 Porous Glass-ceramics
• BIOMIMETIC COATING OF BONE-LIKE APATITE ON GLASS BEADS
• Apatite-forming ability of organic-inorganic hybrids fabricated from glucomannan by chemical modification with alkoxysilane and calcium salt( Ceramics for Biomedical Applications in Asian Countries)
• Effects of Cross-Linking Agent on Apatite-Forming Ability and Mechanical Property of Organic-Inorganic Hybrids Based on Starch
• Brain-Derived Neurotrophic Factor Promotes Neurite Growth and Survival of Antennal Lobe Neurons in Brain from the Silk Moth, Bombyx mori in vitro(Neurobiology)
• Formation of octacalcium phosphate with incorporated succinic acid through gel-mediated processing
• A novel role of L-serine (L-Ser) for the expression of nuclear factor of activated T cells (NFAT)2 in receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclastogenesis in vitro
• Preparation of highly functional artificial bones using the properties of calcium phosphates
• Control of setting behavior of calcium phosphate paste using gelatinized starch
• Fabrication of porous blocks of calcium phosphate through hydrothermal processing under glycine coexistence
• ON QUASI-HADAMARD PRODUCTS OF CERTAIN ANALYTIC FUNCTIONS WITH NEGATIVE COEFFICIENTS
• Effectiveness of an Er:YAG Laser in Etching the Enamel Surface for Orthodontic Bracket Retention
• CERTAIN SUBCLASSES OF MULTIVALENT FUNCTIONS(Study on Geometric Univalent Function Theory)
• Case of congenital esophageal stricture by ganglioneuroma and acro-flexural hyperpigmentation : A coincidence?
• Direct In Vitro Selection of Hemin-Binding DNA Aptamer with Peroxidase Activity
• Chemical Aminoacylation of RNA by an Intermolecular Adenosine Transfer Reaction
• 14.Human placenta feeder layers support undifferentiated growth of primate embryonic stem cells(12th Annual Meeting of the Society of Hard Tissue Biology)
• Hair growth promoting effects of adipose tissue-derived stem cells
• 豚のアルコール性肝障害に対する生物学的に活性なセラミックウォーターの防御作用(病理学)
• コレステロールとコール酸ナトリウム食給餌ラットにおける軽度の肝線維症(病理学)
• Single-molecule Visualization of Binding Modes of Helicase to DNA on PEGylated Surfaces
• Primary Cutaneous Langerhans Cell Histiocytosis Treated with Photochemotherapy
• Development of alginate gel dressing
• Enhancement of Catalytic Activity of Chemically Modified Subtilisin Carlsberg in Benzene by Adjustment of Lyophilization Conditions
• Preparation and characterization of periodic porous frame of hydroxyapatite
• N-methylated β-carbolines protect PC12 cells from cytotoxic effect of MPP^+ by attenuation of mitochondrial membrane permeability change
• Subungual Glomus Tumor : Clinical Manifestations and Outcome of Surgical Treatment
• Formation of Hydroxyapatite Microtubes Assisted with Anatase under Hydrothermal Conditions
• Delivery of small interfering RNA with a synthetic collagen poly (Pro-Hyp-Gly) for gene silencing in vitro and in vivo
• Apatite formation abilities of various carrageenan gels in simulated body environment
• The establishment and characterization of immortalized human dermal papilla cells and their hair growth promoting effects
• PEGylated antibody in organic media(BIOCHEMICAL ENGINEERING)
• THE RADIUS OF $\beta$-CONVEXITY FOR THE CLASSES OF $\lambda$-SPIRALLIKE ORDER $\alpha$ FUNCTIONS (Study on Inverse Problems in Univalent Function Theory)
• THE SUBORDINATION THEOREM FOR $\lambda$-SPIRALLIKE FUNCTIONS OF ORDER $\alpha$ (Inequalities in Univalent Function Theory and Its Applications)
• CARDIOVASCULAR TOLERANCE AND AUTONOMIC NERVOUS RESPONSES IN UNSEDATED UPPER GASTROINTESTINAL SMALL-CALIBER ENDOSCOPY : A COMPARISON BETWEEN TRANSNASAL AND PERORAL PROCEDURES WITH NEWLY DEVELOPED MOUTHPIECE
• In Vitro Selection of Peptide Aptamer Binding to Vitamin B12
• Reduction-Triggered Fluorescence Probe for Peptide-Templated Reactions
• Immobilization of Leukemia Inhibitory Factor (LIF) to Culture Murine Embryonic Stem Cells(CELL AND TISSUE ENGINEERING)
• On weakly $\Phi$-like of order $\alpha$ with respect to certain analytic functions (Conditions for Univalency of Functions and Applications)
• On a broad class of univalent functions (Conditions for Univalency of Functions and Applications)
• Polypeptide aptamer selection using a stabilized ribosome display(METHODS)
• THE RADIUS OF β-CONVEXITY FOR THE CLASSES OF λ-SPIRALLIKE ORDER α FUNCTIONS
• Current states and future views in photodynamic therapy
• PEGylated antibody in organic media
• CERTAIN CLASSES OF MEROMORPHICALLY MULTIVALENT FUNCTIONS WITH TWO FIXED POINTS
• Radius of strongly starlikeness for certain analytic functions (単葉関数論の歴史的定理の新展開について)
• The effect of omeprazole on gastric myoelectrical activity and emptying
• Gallic Acid as a Complexing Agent for Copper Chemical Mechanical Polishing Slurries at Neutral pH
• The Effect of Trunk Stabilization Exercise on the Thickness of the Deep Abdominal Muscles and Balance in Patients with Chronic Stroke
• Stimulation of Osteogenesis in Bone Defects Implanted with Biodegradable Hydroxyapatite Composed of Rod-Shaped Particles under Mechanical Unloading
• Predicting Rotor BVI Loads Inclusive of the Fuselage Effect using an Unstructured Mesh Technique
• Addition of the collagen binding domain of fibronectin potentiates the biochemical availability of hepatocyte growth factor for cutaneous wound healing
• Strategy to reduce carbonate incorporation in the fabrication of hydroxyapatite nanopowders
• Synthesis of Calcium Phosphates Containing Metal Ions and Evaluation of their Catalytic Activity for the Decomposition of Hydrogen Peroxide
• Hydrolysis of active esters of aliphatic carboxylic acids with cyclic dipeptide catalysts consisting of L-histidine and different aliphatic .ALPHA.-amino acids.
• Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid
• 408 STUDIES ON THE THERMAL PROPERTIES OF FABRICS FOR THE KOREAN FOLK CLOTHES
• Organic–Inorganic Composites Designed for Biomedical Applications
• Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid

もっと見る 閉じる

スポンサーリンク