Synthesis of ceramics in MO_<n/2>-SiO_2 systems through sol-gel processing under coexistence of polyethylene glycol and in vitro evaluation of their bioactivity(<Feature> Ceramics for Biomedical Applications in Asian Countries)

スポンサーリンク

概要

• 論文の詳細を見る

• Sol-gel processing from tetraethoxysilane (TEOS) under coexistence of polyethylene glycol (PEG) allows controlled morphology of the formed silica because of the phase separation during the polycondensation of the hydrated sol. The presence of PEG controlled the morphology effective in preparation of the ceramics, even in the CaO-SiO_2 binary system, starting from TEOS and Ca(NO_3)_2. In the present study, some ceramics were prepared using the MO_<n/2>-SiO_2 binary systems, where M is given as Na^+ (n=1), Mg^<2+> (n=2) and Al^<3+> (n=3), through sol-gel processing in the presence of PEG, to compare the compositional changes in the morphology of the ceramics. In the case of NaO_<1/2>-SiO_2, the framework size increased remarkably with increasing amounts of Na^+ in the starting compositions up to 30mol%, while continuous pores of approximately 10μm were observed at 5mol% of Na^+. In the case of MgO-SiO_2, the framework size increased with increasing amounts of Mg^<2+> up to 20mol% in the starting composition. Aggregation of particles with approximately 3μm in size was observed at 25mol% and more. The trend in morphological change with addition of Mg^<2+> was quite similar to that with Ca^<2+>. With AlO_<3/2>-SiO_2, particles were obtained when the starting composition was more than 10mol% Al_<3+>. The size of the particles appeared to decrease with increasing amounts of Al^<3+>. The morphology and phase separation behavior are strongly affected by the charge value of the metal ions, because the number of non-bridging oxygens coordinated to the metal ion increased with increasing charge value in the sol-gel processing. A specimen prepared with starting composition 20NaO_<1/2>・80SiO_2 and heated at 600℃ formed hydroxyapatite on the particle surfaces within 7d after soaking in a simulated body fluid (SBF), suggesting a potential for bioactivity on application of bone repair.

• 社団法人日本セラミックス協会の論文
• 2008-01-01

著者

• KAMITAKAHARA Masanobu

  Graduate School of Environmental Studies, Tohoku University

• OHTSUKI Chikara

  Graduate school of Engineering, Nagoya University

• Kamitakahara Masanobu

  Graduate School Of Environmental Studies Tohoku University

• Kamitakahara Masanobu

  Graduate School Of Environmental Studies Tohoku Univ.

• Ohtsuki Chikara

  Department Of Crystalline Materials Science Graduate School Of Engineering Nagoya University

• Ohtsuki Chikara

  Graduate School Of Engineering Nagoya Univ.

• Ohtsuki C

  Department Of Crystalline Materials Science Graduate School Of Engineering Nagoya University

• Ohtsuki Chikara

  Dep. Of Crystalline Materials Sci. Graduate School Engineering Nagoya Univ.

• Ohtsuki Chikara

  奈良先端科学技術大学院大学 物質創成科学研究科

• KAWACHI Giichiro

  Department of Biomaterials, Faculty of Dental Science, Kyushu University

• Kawabata Koji

  Industrial Technol. Center Of Okayama Prefecture

• Ohtsuki Chikara

  Graduate School Of Engineering Nagoya University

• KAWACHI Giichiro

  Graduate School of Engineering, Nagoya University

• KIKUTA Koichi

  Graduate School of Engineering, Nagoya University

• KIM Ill-Yong

  Graduate School of Engineering, Nagoya University

• CHO Sung-Baek

  Korea Institute of Geosciences and Mineral Resources (KIGAM)

• Kim Ill-yong

  Graduate School Of Engineering Nagoya University

• Kawabata Koji

  Department Of Crystalline Materials Science Graduate School Of Engineering Nagoya University

関連論文

• Synthesis of Bioactive HEMA-MPS-CaCl2 Hybrid Gels: Effects of Catalysts in the Sol-Gel Processing on Mechanical Properties and in vitro Hydroxyapatite Formation in a Simulated Body Fluid
• Protein adsorption on needle-shaped hydroxyapatite prepared by hydrothermal treatment of mixture composed of CaHPO_4・2H_2O and β-Ca_3(PO_4)_2
• Novel Bioceramics of Calcium Phosphates Composed of Rod-shaped Particles(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
• Hydroxyapatite-forming capability and mechanical properties of organic-inorganic hybrids and α-tricalcium phosphate porous bodies
• Evaluation of apatite-forming ability and mechanical property of pectin hydrogels( Ceramics for Biomedical Applications in Asian Countries)
• Fabrication of carbonate apatite block based on internal dissolution-precipitation reaction of dicalcium phosphate and calcium carbonate
• Behavior of β-tricalcium phosphate granules composed of rod-shaped particles in the rat tibia
• Fabrication of hydroxyapatite with controlled morphology in a micro-reactor
• Development of a Bone-Repairing Material Through Hybridization of Biodegradable Polymer with Bone-like Apatite(International Symposium of Maxillofacial and Oral Regenerative Biology in Okayama 2005)
• Pore Structure of Hard Carbon Made from Phenolic Resin Studied by ^Xe NMR
• Structure-Photodynamic Effect Relationships of 24 Glycoconjugated Photosensitizers in HeLa Cells(Medicinal Chemistry)
• Microstructure and Bioresorbable Properties of α-TCP Ceramic Porous Body Fabricated by Direct Casting Method
• Structure and morphology of aminopropyltriethoxysilane-modified TiO_2 nano-particles derived from sol-gel processing of tetraethylorthotitanate
• Novel One-pot Sol-Gel Preparation of Amino-functionalized Silica Nanoparticles
• 11-P-03 Preparation and Properties of Hydroxyapatite Powder with Metal Alkoxide
• Hydrothermal synthesis and characterization of hydroxyapatite from octacalcium phosphate
• Hydrothermal synthesis of hydroxyapatite from octacalcium phosphate : effect of hydrothermal temperature(Aqueous Solution Science for Ceramic Processing II)
• Evaluation of photocatalytic activity of anatase/hydroxyapatite composite granules for environmental purification
• Hydrothermal synthesis of magnetite/hydroxyapatite composite material for hyperthermia therapy for bone cancer
• Formation of needle-like hydroxyapatite by hydrothermal treatment of CaHPO_4・2H_2O combined with β-Ca_3(PO_4)_2
• Induced deposition of bone-like hydroxyapatite on thermally oxidized titanium substrates using a spatial gap in a solution that mimics a body fluid
• Hybridization of silver nanoparticles on hydroxyapatite in an aqueous solution(Aqueous Solution Science for Ceramic Processing II)
• Synthesis of octacalcium phosphate intercalated with dicarboxylate ions from calcium carbonate and phosphoric acid
• Surface Topography Designed to Provide Osteoconductivity to Titanium after Thermal Oxidation
• Formation of hydroxyapatite on ceramics consisting of tricalcium phosphate in a simulated body fluid( Ceramics for Biomedical Applications in Asian Countries)
• Synthesis of ceramics in MO_-SiO_2 systems through sol-gel processing under coexistence of polyethylene glycol and in vitro evaluation of their bioactivity( Ceramics for Biomedical Applications in Asian Countries)
• Preparation of hydroxyapatite porous ceramics with different porous structures using a hydrothermal treatment with different aqueous solutions( Ceramics for Biomedical Applications in Asian Countries)
• Effect of Silane-Coupling Treatment on Thermal Decomposition of Octacalcium Phosphate
• A Composite of Hydroxyapatite with Electrospun Biodegradable Nanofibers as a Tissue Engineering Material(CELL AND TISSUE ENGINEERING, Advances in Biomedical Science and Engineering)
• Control of the Microstructure of Porous Tricalcium Phosphate: Effects of addition of Mg, Zn and Fe (特集 バイオ機能材料・バイオインスパイアード材料)
• 11-O-29 Formation of Octacalcium Phosphate from α-TCP Porous Body
• 11-O-18 Graded Structure on Bioactive Metal Induced by Chemical Surface Modification
• 11-I-01 Bioactivity of MgO-CaO-SiO_2 Porous Glass-ceramics
• BIOMIMETIC COATING OF BONE-LIKE APATITE ON GLASS BEADS
• Apatite-forming ability of organic-inorganic hybrids fabricated from glucomannan by chemical modification with alkoxysilane and calcium salt( Ceramics for Biomedical Applications in Asian Countries)
• Effects of Cross-Linking Agent on Apatite-Forming Ability and Mechanical Property of Organic-Inorganic Hybrids Based on Starch
• Formation of octacalcium phosphate with incorporated succinic acid through gel-mediated processing
• Preparation of highly functional artificial bones using the properties of calcium phosphates
• Control of setting behavior of calcium phosphate paste using gelatinized starch
• Fabrication of porous blocks of calcium phosphate through hydrothermal processing under glycine coexistence
• Temperature-dependent Penetration of Argon Molecules into Ultramicroporous Tunnel of a Fluoroorganic Molecular Crystal with Alteration of Its Unit Cell Size
• Preparation and characterization of periodic porous frame of hydroxyapatite
• Formation of Hydroxyapatite Microtubes Assisted with Anatase under Hydrothermal Conditions
• Apatite formation abilities of various carrageenan gels in simulated body environment
• Reinforcement of carbonate apatite bone substitutes with carbonate apatite by Ca salt introduction
• Fabrication of solid and hollow carbonate apatite microspheres as bone substitutes using calcite microspheres as a precursor
• Stimulation of Osteogenesis in Bone Defects Implanted with Biodegradable Hydroxyapatite Composed of Rod-Shaped Particles under Mechanical Unloading
• Strategy to reduce carbonate incorporation in the fabrication of hydroxyapatite nanopowders
• Synthesis of Calcium Phosphates Containing Metal Ions and Evaluation of their Catalytic Activity for the Decomposition of Hydrogen Peroxide
• Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid
• Organic–Inorganic Composites Designed for Biomedical Applications
• Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid

もっと見る 閉じる

スポンサーリンク