Polypeptide aptamer selection using a stabilized ribosome display(METHODS)
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概要
- 論文の詳細を見る
A newly developed ribosome display protocol was applied to the in vitro selection of polypeptide aptamers to small molecular weight chemicals, 6-[hydroxy(4-nitrobenzyl)phosphonyl]hexanoic acid and vitamin B12, chosen from a peptide library of random sequences. New peptide sequences binding to the targets were found after six rounds of this protocol.
著者
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Liu Mingzhe
Nano Medical Engineering Laboratory Riken
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Ito Yoshihiro
Nano Medical Engineering Laboratory Riken Advanced Science Institute
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WANG Wei
Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute
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HARA Shuta
Nano Medical Engineering Laboratory, RIKEN Advanced Science Institute
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Aigaki Toshiro
Department Of Biological Sciences Tokyo Metropolitain University
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Wang Wei
Nano Medical Engineering Laboratory Riken Advanced Science Institute
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Hara Shuta
Nano Medical Engineering Laboratory Riken Advanced Science Institute
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Aigaki Toshiro
Graduate School of Biological Sciences, Tokyo Metropolitan University
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Shimizu Shigeru
Department of Materials and Applied Chemistry, Graduate School of Science and Technology, Nihon Univ
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Shimizu Shigeru
Department Of Materials And Applied Chemistry Graduate School Of Science And Technology Nihon Univer
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Liu Mingzhe
Nano Medical Engineering Laboratory Riken Advanced Science Institute
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ITO Yoshihiro
Nano Medical Engineering Laboratory
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