Acid Lipase Inhibitor in Chicken Plasma Identified as Apolipoprotein A-I
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概要
- 論文の詳細を見る
We have reported a inhibitor of acid lipases in liver lysosomes and erythrocytes from chickens [M. Fujii et al., Int. J. Biochem., 22, 895-898 (1990)]. In this paper, the properties of the inhibitor were described in comparison with those of apo A-I of chicken. The purified inhibitor migrated with the same mobility on SDS-PAGE as apo A-I, and had a molecular weight of 27,000. The peptide map from the lipase inhibitor was similar to that of apo A-I. Antibodies to the acid lipase inhibitor also reacted with apo A-I. Apo A-I inhibited the acid lipase activities of liver lysosomes and erythrocytes from chickens as strongly as the lipase inhibitor. The N-terminal amino acid sequence of lipase inhibitor was identical to that of apo A-I as far as residue 20. The amino acid sequence of peptides obtained from the inhibitor by cleavage with CNBr corresponded to internal sequence of apo A-I, and so the CNBr-peptides were derived by cleavage after the methionine residues in apo A-I. The findings showed that the inhibitor of the acid lipases in liver lysosomes and erythrocytes from chickens was identical to apo A-I.
- 社団法人日本農芸化学会の論文
- 1996-10-23
著者
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MUKAI Satoru
Department of Hematology, Osaka City General Hospital
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Fujii Mikio
Foods Research Group Foods Division Asahi Chemical Industry Co. Ltd.
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YANO Takahiro
Department of Physics,Faculty of Science,Yamagata University
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Mukai Satoru
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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FUJII Makoto
Department of Biopathological Science, Okayama University Graduate School of Medicine and Dentistry
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Kawaguchi Hiroyuki
Department of Endodontology and Periodontology, Hiroshima University School of Dentistry
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Higuchi Tetsuro
Department of Surgical Oncology, Graduate School of Medicine, Tokyo Medical and Dental University
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SUGIMOTO Yasushi
Department of Food and Nutrition, Seinan-Jogakuin Junior College
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Fujii Michihiko
Kihara Inst. For Biological Res. And Graduate School Of Integrated Sci. Yokohama City Univ.
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Fujii Michihiko
Kihara Institute For Biological Research And Graduate School Of Integrated Science Yokohama City Uni
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Yano Takahiro
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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Yonekura Masami
Food Function Laboratory School Of Agriculture Ibaraki University
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Yamai Masafumi
Division Of Biomolecular Science The Graduate School Of Natural Science And Technology Okayama Unive
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Yonekura Masami
Faculty Of Agriculture Ibaraki University
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Yonekura Masami
Department Of Applied Biological Resource Sciences School Of Agriculture Lbaraki University
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Higuchi Tetsuro
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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NONAKA Koh-ichi
Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University
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FUKUNAGA Takao
Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University
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YAMADA Shoji
Laboratory of Marine Biochemistry, Faculty of Fisheries, Kagoshima University
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Fukunaga Takao
Department Of Animal Science Faculty Of Agriculture Kagoshima University
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Fukunaga Takao
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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Sugimoto Yasushi
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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Fujii Mitsuko
Division Of Bioscience Graduate School Of Natural Science And Technology Okayama University
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Fujii Makoto
Department Of Animal Science Faculty Of Agriculture Kagoshima University
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Nonaka Koh-ichi
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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Yamada Shoji
Laboratory Of Marine Biochemistry Faculty Of Fisheries Kagoshima University
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Kawaguchi Hiroyuki
Department Of Biochemical Science And Technology Faculty Of Agriculture Kagoshima University
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