Anti-thrombotic and Anti-atherogenic Action of Eicosapentaenoic Acid

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概要

• 論文の詳細を見る

• Effects of dietary supplementation with highly purified EPA (1.8-2.7 g/day) for 16 weeks on platelet and red blood cell function and serum lipids concentration were investigated in patients with various thrombotic diseases. Decreases in platelet aggregation, thromboxane formation in platelets, platelet retention and whole blood viscosity, increased red blood cell deformation and prolongation of bleeding time were observed in the present study. In addition a reduction in serum cholesterol and triglyceride concentrations was noted in patients with hyperlipidemia after EPA ingestion. Some clinical improvements such as improvement of diabetic gangrene or peripheral vascular occlusive disease were observed. These results indicate that dietary supplementation of purified EPA may be beneficial for prevention and treatment of cerebro- and cardiovascular diseases.

• 社団法人日本循環器学会の論文
• 1987-04-20

著者

• Tamura Y

  The Second Department Of Internal Medicine Chiba University School Of Medicine

• Terano T

  Chiba Univ. Chiba Jpn

• KITAGAWA HARUO

  Faculty of Pharmaceutical Sciences, Chiba University

• Takenaga Mitsuko

  Faculty Of Pharmaceutical Sciences Chiba University

• Yoshida S

  The Second Department Of Internal Medicine Chiba University School Of Medicine

• Hirai Aizan

  The Second Department Of Internal Medicine Chiba University School Of Medicine

• Kitagawa Haruo

  Faculty Of Pharmaceutical Sciences Chiba University

• TAMURA Yasushi

  The 2nd Department of Int.Med.School of Medicine,Chiba University

• HIRAI AIZAN

  The 2nd Department of Internal Medicine, Chiba University Medical School

• TERANO TAKASHI

  The 2nd Department of Internal Medicine, Chiba University Medical School

• YOSHIDA SHO

  The 2nd Department of Internal Medicine, Chiba University Medical School

• Kitagawa H

  Faculty Of Pharmaceutical Sciences Chiba University

• Yoshida S

  Sharp Corp. Nara Jpn

• Tamura Yasushi

  The 2nd Department Of Int.med.school Of Medicine Chiba University

• TAMURA YASUSHI

  The 2nd Deartment of Internal Medicine, Chiba University School of Medicine

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