小児気管支喘息のアレルゲン診断と特異療法に関する研究 : 2.絹による吸入性喘息

概要

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Silk is employed as the finest dressing and stuffing materials for bedclothing. Therefore it appears possible that one may inhale silk and become sensitized. We reported 4 cases of such asthma induced by silk, in 1964. In this paper, we present 9 cases of bronchial asthma induced by silk. Clinical observations of these silk asthma are summarized as follows: A. History. In most cases, a clear relationship was found between asthmatic attacks and silk inhalation. B. Skin test with silk extract showed a strongly positive reaction. C. Provocative test. Asthma was induced by inhalation of silk extracts or use of the pillow stuffed with raw silk. D. Avoidance. The attacks of asthma stopped after avoidance of silk products. E. Hyposensitization therapy with silk extract was effective. In summary, several interesting points have been noticed about asthma due to silk inhalation. First, the asthmatic attacks stopped as soon as the silk material was avoided. This characteristic has also been found in the case of asthma caused by buckwheat inhalation. Secondly, since the use of silk is rather limited, it seemed not difficult to have suspicion of silk asthma by recognizing the relationship between the asthmatic attack and exposure to silk. Thirdly, as already described, silk has a strong antigenicity, and a positive reaction can be obtained even with 1:100,000,000 dilution of silk extract.
日本アレルギー学会の論文
1969-11-30