食餌アレルギーの研究 : 第6報.大豆アレルギー.

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Authors reported on 42 cases of soybean allergy using elimination and trial ingestion diets. These were as follows: Urticaria 4, headache 6, abdominal pain 2, diarrhea 1, constipation 1, eczema 6, bronchial asthma 6, cyclic vomiting 5, orthostatic albuminuria 10 and purpura 1. The following summary was obtained from these cases. 1) The period up to the disappearance of symptoms after starting elimination of soybean was short in diseases or symptoms such as urticaria, headache, abdominal pain, diarrhea, constipation (A group), while it was relatively long in eczema, bronchial asthma and cyclic vomiting (B group) as well as orthostatic albuminuria (C group). 2) The period necessary for eliciting symptoms by the trial ingestion of soybean seemed to be shorter in A) C) group than in B) group. 3) The close relationship seemed to exist between the period necessary for the disappearance of symptoms after the elimination of soybean and for the appearance of symptoms by the trial ingestion in patients with soybean allergy. 4) On the provocative test, a great deal of symptoms were accompanied with the occurrence of the original disease. Those seemed to be much more in the B) C) group than in A) group. 5) There were other food allergens together with soybean, all of which caused similar symptoms in the same case. These allergens were milk in 11 cases, egg in 6, milk and egg in 6, and egg, tuna and buckwheat in 1. 6) Period of elimination, which resulted finally in no symptoms on provocative test even though respective and causative food was given, was longer in soybean allergy than either in milk or egg allergy. 7) Out of 42 cases, symptoms caused by the soybean allergen were also provoked with red bean in 5 cases, and with peas in one so that cross reactivity was clinically found to exist among them. 8) On the intracutaneous test with soybean extract positive reaction was observed in 13 of 20 cases (65 per cent). In this way, it was shown that there were many of the clinical cases due to allergy to soybean so that soybean should be considered to be one of the most important food allergens in Japan.
日本アレルギー学会の論文
1967-12-30

食餌アレルギーの研究 : 第6報.大豆アレルギー.

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