イネ花粉喘息の研究 : 第2報・イネ花粉と他のイネ科花粉との間の共通抗原に関する研究

概要

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In the previous paper, authors reported that rice pollen was considered as one of the important inhalant allergens to cause asthmatic attacks in early fall in Japan. However, a problem remains to be solved as to whether hypersensitivity to rice pollen can be produced by the exposure to rice pollen itself or to other grass pollens which presumably cross react with it and are grown or cultivated widely in Japan. In the present paper, cross antigenicity was examined by means of passive transfer-in vivo and -in vitro neutralization test as well as in vitro neutralization test by using PCA reaction in monkey and guinea pig, between rice pollen and other grass pollens including wheat, orchard grass, timothy, corn and pumpus grass pollens. As result, it was demonstrated that weak cross antigenicity exists between rice pollen and pollens of wheat, orchard grass and timothy, but none between rice pollen and corn pollen as well as pumpus grass pollen. From these results, it seems reasonable to conclude that hypersensitivity to rice pollen foud in asthmatic children could be attributable mainly to rice pollen itself which floats abundantly from late summer to early fall in Japan.
日本アレルギー学会の論文
1969-12-30