MUTAGENICITY OF BOVINE LACTOFERRIN IN REVERSE MUTATION TEST
スポンサーリンク
概要
- 論文の詳細を見る
The mutagenicity of bovine lactoferrin, which is an iron-binding glycoprotein in milk, was evaluated by the Ames mutagenicity test. A total of 5 test strains including 3 base-pair substitution-type strains, Salmonella typhimurium TA100, TA1535 and Escherichia coli WP2uvrA, and 2 frameshift-type strains, TA98 and TA1537, were used in the test. The test was performed by both the direct method and the metabolic activation method with preincubation applied in each instance. The concentration range of the test solution was 0.16 to 5.00 mg / 100μl (plate). Results of the test revealed that the number of revertant colonies at each concentration of the test solutions was less than 1.4 times that of the control group. In the test system used, bovine lactoferrin did not exhibit mutagenicity.
- 日本トキシコロジー学会の論文
- 2000-05-11
著者
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Teraguchi S
Morinaga Milk Ind. Co. Ltd. Kanagawa Jpn
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Teraguchi Susumu
三重大学保健管理センター
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Yamauchi Koji
Nutritional Science Laboratory Morinaga Milk Industry Co. Ltd.
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Teraguchi Susumu
Nutritional Science Laboratory, Morinaga Milk Industry Co., Ltd
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TOIDA Tomohiro
Biochemical Research Laboratory, Morinaga Milk Industry Co., Ltd.
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KAWAI Akihiro
Japan Automobile Research Institute
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NISHIMURA Susumu
Gotenba Laboratory, Bozo Research Center Inc.
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HAYASAWA Hirotoshi
Nutritional Science Laboratory, Morinaga Milk Industry Co., Ltd.,
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Toida Tomohiro
Biochemical Research Laboratory Morinaga Milk Industry Co. Ltd.
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Yamauchi Koji
Toxicologic Pathology Drug Safety Research Laboratories Astellas Pharma Inc.
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Hayasawa Hirotoshi
Nutritional Science Laboratory
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Hayasawa Hirotoshi
Nutritional Science Laboratory Morinaga Milk Industry Co. Ltd. :biochemical Research Laboratory Mori
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Yamauchi Koji
Nutritional Science Institute Morinaga Milk Industry Co. Ltd.
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Teraguchi Susumu
Nutritional Science Laboratory Morinaga Milk Industry Co. Ltd.
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Teraguchi Susumu
Nutritional Science Laboratory
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Toida Tomohiro
Food Sci. & Technol. Inst. Morinaga Milk Ind. Co. Ltd.
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