コアグラーゼ-エンテロトキシン型別で分類した MRSA に対する各種消毒剤の殺菌効果

概要

論文の詳細を見る
The bactericidal effect of four kinds of disinfectant-benzethonium chloride, benzalkonium chloride, chlorhexidine gluconate and alkyl diaminoethyl glycine-was evaluated against 30 strains of Staphylococcus aureus which comprised of 24 strains of Methcillin-resistant Staphylococcus aureus (MRSA) and six of Methicillin-sensitive Staphylococcus aureus (MSSA). The effect was measured by the phenol coefficient method and the MRSA strains were classified by type-combination of coagulase and enterotoxin as IIA, IIB, IIC and IINT (non-typable) The results were as follows: 1) All strains except for three strains of MRSA and MSSA became growth-inhibited within 15 seconds due to each disinfectant at a rate of 0.1% which was the ordinary dose in clinical use. 2) There were differences in inhibition time by 0.02% of the disinfectants among the MRSA type-combinations. So far as our materials were concerned, we concluded that there was no necessity to distinguish MRSA from MSSA when "disinfection" is considered.
日本医療薬学会の論文
1995-04-10