輸液中における細菌の消長に関する実験的研究

概要

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Several infusion solutions, such as 5% Dextrose injection, Hartman's D solution^<[○!R]>, proteamin XT^<[○!R]> and IVH solution, were experimentally incubated with Staphylococcus aureus, Escherichia coil, Klebsiella pneumoniae, Psuedomonas aeruginosa, and Candida albicans, and were examined for bacterial growth for 24 hr. No bacterial growth was observed in these infusion solutions for 6 hr. Further, the admixtures with several vitamin intravenous solutions were also examined. Although some interbacterial variance was observed, no bacterial growth was observed in the admixtures for 24 hr. Among the bacteria examined in this study, Candida albicans was most potential for survival. These results revealed that once bacterial contamination had occurred during preparation of these infusion solutions, bacteria would survive until the completion of infusion. So we conclude that the methods and the environment involved the preparation of infusion solutions should be carefully monitored in order to minimize bacterial contamination.
日本医療薬学会の論文
1983-10-20