ラット三叉神経脊髄路核におけるFos発現に対するハリ通電刺激の抑制効果

概要

論文の詳細を見る
We investigated whether, or not. expression of c-fos (an immediate-early gene) and amplitude of jaw opening reflex evoked by noxious stimulation were influenced under electro-acu-puncture by means of immunohistochemistry and electromyogram in urethan-anasthetized rats. The noxious electrical pulses (0.2 Hz) were delivered to unilateral buccal area for 30 min. Expression of Fos (c-fos protein) was induced in the spinal trigeminal nucleus 30 min after the noxious stimulation. Amplitude of jaw opening reflex and number of Fos-expressing neurons were deccreased to 39% and 70% of control, respectively, by electro-acupuncture which was treated with unilateral forelimb at 3.0 Hz before 30 min of the noxious stimuli and during. These results suggest that Fos expression and jaw opening reflex evoked by noxious stimuli are, in part, inhibited by electro-acupuncture.
関西鍼灸大学の論文
1995-10-25