脂肪酸組成の異なる油脂投与のラット血清,肝臓,脾臓の鉄濃度に及ぼす影響(自然科学編)

概要

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We aimed to investigate the relationship between serum and liver iron concentration and the kind of dietary fatty acid. Young male rats were fed the diet containing different fat (coconut oil, olive oil, safflower oil and perilla oil) for 3 weeks. The iron concentration of serum, liver and spleen of perilla oil group were significantly lower than those of coconut oil group, and this decreasing tendency was increased the perilla oil, safflower oil, olive oil and coconut oil group in that order. The concentrations of unsaturated iron binding capacities (UIBC) and serum ferritins were not observed the significant difference among all dietary groups. The serum iron concentration was showed opposite tendency for the plasma lipid peroxide value, increasing the tendency in order of the coconut oil, olive oil, safflower oil and perilla oil groups. It was postulated that, by the dose of higher degree unsaturated fatty acid such as n-3 polyunsaturated fatty acids, as the plasma lipid peroxide was increased, the serum iron concentration of serum, liver and spleen was decreased.
千葉県立衛生短期大学の論文