<論文>肥満症に対する運動療法 : 実験的肥満ラットの体重および脂質代謝に対するwalkingの効果

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The present study attempted to demonstrate the effects of walking exercise on body weight, lipid metabolism and serum enzymes in experimental obesities induced by ventromedial hypothalamic (VMH) lesions. The rats were then divided into VMH-lesioned and Sham operated sedentary groups (Sham-S). After 3 weeks, VMH-lesioned rats were then divided into a treadmill walking group (VMH-W, 10m/min, 60min) and a sedentary group (VMH-S) for 6 weeks. The body weights at the end of the experiments were remarkably greater (P<0.01) in VMH-W and S than that Sham-S. The body weitht in VMH-W wassignificantly lower (P<) than that in VMH-S. The concentration of serum trglyceride (TG) in VMH-S was markedly higher (P<0.05) than that in Sham-S. The serum TG in VMH-W tended to be lower than that in VMH-S. Changes in the serum cholesterol (Cho) was also similar to those of serum TG. Hepatic TG and Cho in VMH-S and W were significantly higher than Sham-S. The serum glutamic pyruvic transaminase and cholinesterase in VMH-W and S were markedly higher (P<0.01) than those of Sham-S. It is thus concluded that walking exercise might be effective in effective in body weight and lipid increasing metabolism normalizing, and it also may be used effectively in the body weight reduction and/or clinical treatment for obesity.
東海大学の論文
1989-03-31