ラットの体内脂質・リポ蛋白代謝におよぼす無コレステロール食および運動負荷の影響

概要

論文の詳細を見る
In order to accelerate the syntheses of triglyceride (TG) and very low density lipoprotein cholesterol (VLDL-Cho.), the Wistar strain rats were fed with 10% sucrose solution and normal food for 5 weeks. The animals were fed again with cholesterol-free diet with normal water for 5 weeks, thereafter, we examined the changes in the level of serum lipids and lipoprotein metabolism and the effect on the long-term endurance exercise. The concentrations of the TG and VLDL-Cho. were significantly higher in sucrose ingested group than the control. After stopping of sucrose supply these values fell down to the control level by 5 weeks in cholesterol-free and non-exercise group. The diminution of the TG and VLDL-Cho. concentrations were clearly shown after feeding with cholesterol-free diet under such condition as a hyperlipidemia. It is known that the soybean protein, unsaturated fatty acids, and dieting fiber have an inclination to decrease the TG and VLDL-Cho. contents. These compositions of the food used in this study may affect the TG and VLDL-Cho. levels. Moreover the simultaneous endurance exercise decreased on both values. The results show that the endurance exercise and pertinent diet at the same time will contribute to the alleviation of hyperlipidemia.
東海大学の論文