Down-regulation in Multiple Human Cancers of a Novel Gene, DMHC, from 17q25.1 That Encodes an Integral Membrane Protein
スポンサーリンク
概要
- 論文の詳細を見る
- 2001-04-30
著者
-
Tsuneizumi Michiko
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Emi Mitsuru
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Nagai Hisaki
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Harada Haruhito
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Emi M
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
NOBE Yukiko
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School
-
Nagai H
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
Nagai Hisaki
日本医科大学老人病研究所
-
Nagai H
Department Of Surgery Tokyo Women's Medical University Daini Hospital
-
Nagai Hisaki
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
Harada Haruhito
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
Harada Haruhito
日本医科大学老人病研究所
-
Harada Haruhito
Division Of Cardiovascular Disease Kurume University Medical Center
-
Tanaka Shigeo
Department Of Disease Control And Homeostasis Kanazawa University
-
Tanaka Shigeo
日本医科大学 病理
-
Tanaka S
Division Of Thoracic Surgery Department Of Surgery Nippon Medical School
-
Sugano Sumio
放射線医学総合研究所
-
Sugano Sumio
Helix Research Institute
-
Koizumi Kiyoshi
日本医科大学 呼吸器外科
-
Sugano Sumio
Department Of Virology Institute Of Medical Science University Of Tokyo
-
KOIZUMI Kiyoshi
Department of Radiology, Hachioji Medical Center, Tokyo Medical University
-
Tanaka Shigeo
Division Of Thoracic Surgery Department Of Surgery Nippon Medical School
-
Emi Mitsuru
Department Of Biochemistry Cancer Institute
-
MIKAMI Iwao
Department of Biological Regulation and Regenerative Surgery, Nippon Medical School
-
Sugano Sumio
University Of Tokyo
-
Sugano Sumio
Department Of Virology
-
Tanaka Shigeo
Department Of Anatomy Nihon University School Of Dentistry At Matsudo
-
Nishi Hirofumi
Nishi Hospital
-
Nishi Hirofumi
Cardiovascular Center Kurume University
-
Nobe Yukiko
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
TANAKA SHICEO
2nd Surg. Dept. Nihon Med. School
-
Emi Mitsuru
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Mikami Iwao
Division Of Thoracic Surgery Department Of Surgery Nippon Medical School
-
Mikami Iwao
日本医科大学 外科学(内分泌･心臓血管･呼吸器部門)
-
Tanaka Shigeo
The Department Of Surgery Ii Division Of Cardiovascular Surgery Nippon Medical School
-
Koizumi Kiyoshi
Department Of Cardiovascular Surgery Saiseikai Utsunomiya Hospital
-
Mikami Iwao
Genome Science Division University Of Tokyo
-
Tsuneizumi Michiko
Department Of Molecular Biology Institute Of Gerontology Nippon Medical School
-
Tanaka Shigeo
Division Of Diagnostic Pathology Nippon Medical School Hospital
-
Takeshima Shigeto
Department Of Surgery Ii National Defense Medical College
-
Tamai Seiichi
Division Of Diagnostic Pathology Nippon Medical School Hospital
-
Harada Haruhito
Department of Cardiology, Kurume University Medical Center
関連論文
- Overrepresentation of the EBAG9 Gene at 8q23 Associated with Early-Stage Breast Cancers
- Down-regulation of members of glycolipid-enriched membrane raft gene family, MAL and BENE, in cervical squamous cell cancers
- Genetic Association of Low-Density Lipoprotein Receptor-Related Protein 2 (LRP2) with Plasma Lipid Levels
- Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia
- Hypercholesterolemia associated with splice-junction variation of inter-α-trypsin inhibitor heavy chain 4 (ITIH4) gene
- A promoter SNP (-1323T>C) in G-substrate gene (GSBS) correlates with hypercholesterolemia
- Hypertriglyceridemia associated with amino acid variation Asn985Tyr of the RP1 gene
- G-substrate gene promoter SNP (-1323T>C) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia : Intra-familial association study in an eight-generation hyperlipidemic kindred
- Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia : intrafamilial association study in an eight-generation hyperlipidemic kindred
- Interaction between the LDL-receptor gene bearing a novel mutation and a variant in the apolipoprotein A-II promoter : molecular study in a 1135-member familial hypercholesterolemia kindred
- Characterization of liver-cirrhosis nodules by analysis of gene-expression profiles and patterns of allelic loss
- Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity
- Three Distinct Commonly Deleted Regions of Chromosome Arm 16q in Human Primary and Metastatic Prostate Cancers
- Localization of a Tumor Suppressor Gene Associated With Progression of Human Prostate Cancer Within a 1.2 Mb Region of 8p22-p21.3
- A 3-Mb Physical Map of the Chromosome Region 8p21.3-p22,Including a 600-kb Region Commonly Deleted in Human Hepatocellular Carcinoma, Colorectal Cancer, and Non-Small Cell Lung Cancer
- Clinical variant of Tangier disease in Japan : mutation of the ABCA1 gene in hypoalphalipoproteinemia with corneal lipidosis
- Allelic Losses of Loci at 3p25.1,8p22,13q12,17p13.3,and 22q13 Correlate with Postoperative Recurrence in Breast Cancer
- Segmental Copy Number Loss of SFMBT1 Gene in Elderly Individuals with Ventriculomegaly: A Community-Based Study
- Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma
- Identification of a 1-Mb Common Region at 16q24.1-24.2 Deleted in Hepatocellular Carcinoma
- Allelic Loss at 1p34,13q12,17p13.3,and 17q21.1 Correlates With Poor Postoperative Prognosis in Breast Cancer
- Identification of a 1-cM Region of Common Deletion on 4q35 Associated With Progression of Hepatocellular Carcinoma
- Correlation of Allelic Loss with Poor Postoperative Survival in Breast Cancer
- PTEN/MMAC1 Mutations in Hepatocellular Carcinomas: Somatic Inactivation of Both Alleles in Tumors
- Frequent Allelic Loss at 6q26-27 in Breast Carcinomas of the Solid-tubular Histologic Type
- Detailed Deletion Mapping of Chromosome Arm 3p in Breast Cancers : A 2-cM Region on 3p 14.3-21.1 and a 5-cM Region on 3p 24.3-25.1 Commonly Deleted in Tumors
- Correlation of Allelic Losses and Clinicopathological Factors in Primary Breast Cancers
- Mapping of a Breast Cancer Tumor Suppressor Gene Locus to a 4-cM Interval on Chromosome 18q21
- Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray
- Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers
- Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers
- Upregulation and Overexpression of Human X-box Binding Protein 1 (hXBP-1) Gene in Primary Breast Cancers
- Amplification, up-regulation and over-expression of DVL-1, the human counterpart of the Drosophila disheveled gene, in primary breast cancers
- Ret/PTC3 is the most frequent form of gene rearrangement in papillary thyroid carcinomas in Japan
- Allelic Loss on Chromosome 9q Is Associated with Lymph Node Metastasis of Primary Breast Cancer
- Nucleotide variations in genes encoding plasminogen activator inhibitor-2 and serine proteinase inhibitor B10 associated with prostate cancer
- Association of common missense changes in ELAC2 (HPC2) with prostate cancer in a Japanese case-control series
- Genomic Structure and Mapping of Human Orphan Receptor LXR Alpha : Upregulation of LXRa mRNA During Monocyte to Macrophage Differentiation
- Genetic Association between Aldehyde Dehydrogenase 2 (ALDH2) Variation and High-Density Lipoprotein Cholesterol (HDL-C) Among Non-Drinkers in Two Large Population Samples in Japan
- Association of an intronic haplotype of the LIPC gene with hyperalphalipoproteinemia in two independent populations
- Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
- Correlation of Allelic Losses and Clinicopathological Factors in 504 Primary Breast Cancers
- Association of Allelic Losses at 3p25.1, 13q12, or 17p13.3 with Poor Prognosis in Breast Cancers with Lymph Node Metastasis
- Allelic Loss at 1p34-36 Predicts Poor Prognosis in Node-negative Breast Cancer
- DNA alterations during multi-step development of human hepatocellular carcinomas revealed by laser capture microdissection
- Genomic structure of the gene encoding human 3-hydroxy-3-methyl-glutaryl coenzyme A reductase : comparison of exon/intron organization of sterol-sensing domains among four related genes
- Genomic structure and chromosomal mapping of the human sterol regulatory element binding protein (SREBP) cleavage-activating protein (SCAP) gene
- Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers
- Definition of a 1-Mb homozygous deletion at 9q32-q33 in a human bladder-cancer cell line
- Two Target Regions of Allelic Loss on Chromosome 9 in Urinary-bladder Cancer
- Mapping of a New Target Region of Allelic Loss to a 6-cM Interval at 21q21 in Primary Breast Cancers
- Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas
- Molecular cloning, tissue expression, and chromosomal assignment of a novel gene encoding a subunit of the human signal-recognition particle
- Association of single nucleotide polymorphisms in the promoter region of the pro-opiomelanocortin gene (POMC) with low bone mineral density in adult women
- Association of a single-nucleotide polymorphism in the promoter region of leukemia inhibitory factor receptor gene with low bone mineral density in adult women
- Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene
- Association of a single-nucleotide polymorphism in low-density lipoprotein receptor-related protein 5 gene with bone mineral density
- Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women
- Association of natural tooth loss with genetic variation at the human matrix Gla protein locus in elderly women
- Association of the -381T/C promoter variation of the brain natriuretic peptide gene with low bone-mineral density and rapid postmenopausal bone loss
- Thirteen single-nucleotide polymorphisms in the human osteopontin gene identified by sequencing of the entire gene in Japanese individuals
- Linkage disequilibrium and haplotype analysis among ten single-nucleotide polymorphisms of interleukin 11 identified by sequencing of the gene
- Genomic structure and chromosomal mapping of the human Site-1 protease (S1P) gene
- Isolation and radiation hybrid mapping of a highly polymorphic CA repeat sequence at the SREBP cleavage-activating protein (SCAP) locus
- Two Distinct Commonly Deleted Regions on Chromosome 13q Suggest Involvement of BRCA2 and Retinoblastoma Genes in Sporadic Breast Carcinomas
- PRLTS Gene Alterations in Human Prostate Cancer
- A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density
- Association of bone mineral density with a dinucleotide repeat polymorphism at the calcitonin (CT) locus
- Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis
- Association of bone mineral density with polymorphism of the human matrix Gla protein locus in elderly women
- The important role for βVLDLs binding at the fourth cysteine of first ligand-binding domain in the low-density lipoprotein receptor
- Down-regulation in Multiple Human Cancers of a Novel Gene, DMHC, from 17q25.1 That Encodes an Integral Membrane Protein
- Identification of DMC1, a novel gene in the TOC region on 17q25.1 that shows loss of expression in multiple human cancers
- Genomic organization and chromosomal mapping of ELKS, a gene rearranged in a papillary thyroid carcinoma
- Eight novel mutations and functional impairments of the LDL receptor in familial hypercholesterolemia in the north of Japa
- Apolipoprotein H Variant Modifies Plasma Triglyceride Phenotype in Familial Hypercholesterolemia : A Molecular Study in an Eight-generation Hyperlipidemic Family
- Three Aberrant Splicing Variants of the HMGIC Gene Transcribed in Uterine Leiomyomas
- Frequent Allelic Loss at 7p14-15 Associated with Aggressive Histologic Types of Breast Cancer
- Mapping of a New Target Region of Allelic Loss to a 2-cM Interval at 22q 13.1 in Primary Breast Cancer
- Novel single nucleotide polymorphisms of the human nuclear factor kappa-B 2 gene identified by sequencing the entire gene
- Novel single nucleotide polymorphisms of the human colony-stimulating factor 2 (CSF2) gene identified by sequencing the entire gene
- Five novel single-nucleotide polymorphisms of human interferon gamma identified by sequencing the entire gene
- Five familial hypercholesterolemic kindreds in Japan with novel mutations of the LDL receptor gene
- Familial Hypercholesterolemia with Cholesteryl Ester Traansfer Protein Deficiency
- Association of estrogen receptor β (ESR2) gene polymorphism with blood pressure
- Isolation and radiation hybrid mapping of a highly polymorphic CA repeat sequence at the human nuclear factor kappa-beta subunit 1 (NFKB1) locus
- Fusion of a Novel Gene, ELKS, to RET Due to Translocation t(10;12)(q11;p13) in a Papillary Thyroid Carcinoma
- Co-segregation of elevated LDL with a novel mutation (D92K) of the LDL receptor in a kindred with multiple lipoprotein abnormalities
- A novel LDLR mutation, H190Y, in a Utah kindred with familial Hypercholesterolemia
- Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes : genomic structure and seven polymorphisms of the FAP-1 gene
- Genomic structure and eight novel exonic polymorphisms of the human N-cadherin gene
- Allelic Loss on Chromosome 1p Is Associated with Progression and Lymph Node Metastasis of Primary Breast Carcinoma
- Overestimated frequency of a possible emphysema-susceptibility allele when microsomal epoxide hydrolase is genotyped by the conventional polymerase chain reaction-based method
- Association of diffuse panbronchiolitis with microsatellite polymorphism of the human interleukin 8 (IL-8) gene
- The c-Jun NH_2-terminal kinase3 (JNK3) gene : genomic structure, chromosomal assignment, and loss of expression in brain tumors
- Nine novel single-nucleotide polymorphisms in the integrin β4 (ITGB4) gene in the Japanese population
- Linkage disequilibrium and haplotype analysis among eight novel single-nucleotide polymorphisms in the human tissue-type plasminogen activator (t-PA) gene
- Human calcitonin receptor-like receptor for adrenomedullin : genomic structure, eight single-nucleotide polymorphisms, and haplotype analysis
- Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability
- Frameshift Mutations and a Length Polymorphism in the hMSH3 Gene and the Spectrum of Microsatellite Instability in Sporadic Colon Cancer