A Hair Growth-Promoting Effect of Chinese Black Tea Extract in Mice
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概要
- 論文の詳細を見る
Chinese black tea extract (CBTE) fermented with Aspergillus sp. significantly promoted hair growth after 2 weeks of topical application in shaved 6 week-old male C3H/He mice. The hair growth-promoting effect of CBTE was potentiated synergistically by capsaicin, which has no effect on hair growth by itself. CBTE displayed an affinity for estrogen receptor (ER)α, with an IC50 value of 74.8 µg/mL. This effect of CBTE might be mediated by the ERs, since a similar effect induced by orally administered soy isoflavone, a mixture of ERs ligands, has been reported to be synergistically potentiated by capsaicin.
著者
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Yoshikawa Masaaki
Division Of Food Bioscience And Biotechnology Graduate School Of Agriculture Kyoto University
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YANO Yoshihisa
Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan
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FUJITA Hiroyuki
Research and Development Department, Nippon Supplement, Inc.
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HOU I-Ching
Research and Development Department, Nippon Supplement, Inc.
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OI Yasuyuki
Research and Development Department, Nippon Supplement, Inc.
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FUKAMI Harukazu
Graduate School of Bioenvironmental Science, Kyoto Gakuen University
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YANO Yoshihisa
Graduate School of Bioenvironmental Science, Kyoto Gakuen University
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