An Important Role of Prostacyclin in Porcine Thyroid Cells In Culture: Augmentation of Prostacyclin by TSH in Culture, Increase of Prostacyclin after Acute TSH-stimulation in TSH Treated Cells and Stimulation of c AMP Synthesis and Iodine Metabolism by Pr

概要

論文の詳細を見る
Cultured porcine thyroid cells produce PGE2, PGF2α , TXA2 and PGI2. PGE2 and PGI2 stimulate c AMP synthesis and iodine metabolism. When cultured in the presence of TSH, the cells produce PGI2 and when cultured in the absence of TSH, the cells produce PGE2, PGF2α , and TXA2. TSH acutely stimulates PGE2 and PGI2 syntheses. When cultured in the presence of TSH, TSH acutely stimulates PGI2 synthesis and when cultured in the absence of TSH, TSH acutely stimulates PGE2 synthesis. In the presence of TSH, PGI2 plays more important role than other PGs.