.ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XXI. A novel synthesis of .ALPHA.-dehydroamino acid derivatives by the Arbusov reaction of .ALPHA.-phosphoranylideneamino-2-alkenoates.
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概要
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The reaction of ethyl 2-azido-2-alkenoate with organic tervalent phosphorus reagent gave the corresponding 2-phosphoranylideneamino derivative as an stable intermediate. This transformed gradually at room temperature, or immediately on a silica-gel column to give the corresponding 2-phosphinylamino derivative in a good yield. The Arbusov reaction of the intermediate which occurred during the transformation was found to be applicable for the other azido olefins. The formation mechanism and the configurational determination of the new products are discussed.
- 公益社団法人 日本化学会の論文
著者
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SHIN Chung-gi
Laboratory of Organic Chemistry, Faculty of Technology, Kanagawa University
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Shin Chung-gi
Laboratory Of Oraganic Chemistry Faculty Of Engineering Kanagawa University
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Yonezawa Yasuchika
Laboratory Of Oraganic Chemistry Faculty Of Engineering Kanagawa University
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Watanabe Kazuhiro
Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter
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Yoshimura Juji
Laboratorium für Organische Chemie Technische Hochschule Tokyo
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