Novel Synthesis of the Main Central 2,3,6-Trisubstituted Pyridine Skeleton [Fragment A-B-C] of a Macrobicyclic Antibiotic, Cyclothiazomycin

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概要

• 論文の詳細を見る
• Chemical Society of Japanの論文
• 2002-07-15

著者

• Shin C‐g

  Kanagawa Univ. Yokohama

• Shin C‐g

  Kanagawa Univ. Yokohama Jpn

• Ito A

  Laboratory Of Organic Chemistry Faculty Of Engineering Kanagawa University

• SHIN Chung-gi

  Laboratory of Organic Chemistry, Faculty of Technology, Kanagawa University

• Yonezawa Yasuchika

  Laboratory of Organic Chemistry, Faculty of Technology, Kanagawa University

• ITO Akio

  Laboratory of Organic Chemistry, Faculty of Technology, Kanagawa University

• Ito Akinori

  Laboratory Of Organic Chemistry Faculty Of Engineering Kanagawa University

• Shin Chung-gi

  Laboratory Of Oraganic Chemistry Faculty Of Engineering Kanagawa University

• Okabe Akihiro

  Laboratory Of Organic Chemistry Faculty Of Engineering Kanagawa University

• Yonezawa Yasuchika

  Laboratory Of Organic Chemistry Faculty Of Engineering Kanagawa University

• Yonezawa Yasuchika

  Laboratory Of Oraganic Chemistry Faculty Of Engineering Kanagawa University

• Yonezawa Yasuchika

  Laboratory of Organic Chemistry, Faculty of Engineering, Kanagawa University

• Ito Akio

  Laboratory of Organic Chemistry, Faculty of Engineering, Kanagawa University

• Shin Chung-gi

  Laboratory of Chemistry for Natural Products, Faculty of Science, Tokyo Institute of Technology

関連論文

• Convenient Synthesis of a 2,3,6-Tristhiazolyl-substituted Pyridine Skeleton[Fragment A-C]of a Macrocyclic Antibiotic,GE 2270 A
• Useful Synthesis of 2,3,6-Tri- and 2,3,5,6-Tetrasubstituted Pyridine Derivatives from Aspartic Acid
• Useful Synthesis of the Main Central 2,3,6-Trisubstituted Pyridine Skelton of Various Thiostrepton-Type Macrocyclic Antibiotics (Heterocycles 30th in Anniversary Issue)
• Total Synthesis of a Macrocyclic Antibiotic, Micrococcin P_1
• Total Synthesis of a Macrocyclic Antibiotic, Micrococcin P
• Convenient Synthesis of the Central 3,6-Di(2-thiazolyl)-2-(4-thiazolyl)-pyridine Skeleton of a Macrocyclic Antibiotic, GE 2270 A
• Synthesis of a Fragment A Derivative of an Antibiotic, Nosiheptide
• Total Synthesis of Antibiotic, Micrococcin P, from 2, 3, 6-Polythiazolesubstituted Pyridine Skeleton[Fragment A-C]
• Synthesis of the Central Heterocyclic Skeleton of an Antibiotic, A10255
• Useful Synthesis of 2, 3, 6-Polythiazolesubstituted Pyridine Skeleton [Fragment A-C]of Peptide Antibiotic, Micrococcin P
• Dehydrooligopeptides. XIV. Syntheses of 2-[(Z)-1-Amino-1-alken-1-yl]oxazole-4-carboxylic Acid and the Main Common Skeleton of Thiostrepton Peptide Antibiotics, A10255G and J^
• Syntheses of 2-[(1S,3S)-1-Amino-3-carboxy-3-hydroxypropyl]-thiazole-4-carboxylic Acid and the Tripeptide Skeleton of Nosiheptide Containing the Acid
• Dehydrooligopeptides. XVII. Practical Syntheses of All of the Diastereomers of N,N-Protected 2,3-Diaminobutanoic Acids from L-and D-Threonine Derivatives
• A Convenient Synthesis of Methyl 2-[2-(Amino)ethenyl-bithiazolyl] thiazoline-4-carboxylate, an Important Skeleton of Cyclothiazomycin
• Synthesis of a Common Main Skeleton of Thiostrepton Peptide Antibiotics, A 10255G and J
• Practical Synthesis of Oligodehydroalanine Derivatives by Repetition of Stepwise Elongation of Serine Derivative and β-Elimination
• Practical Synthesis of Oxazoles Incorporated in α-Dehydroamino Acid and Dehydropeptide Structures
• Convenient Syntheses of Thiazoles Incorporated with α-Dehydroamino Acid and Dehydropeptide Structures
• Total Synthesis of Bistratamides G and H from Various Kinds of ΔAla and ΔAbu-Containing Oligopeptides
• New Total Synthesis of Dendroamide A from Dehydrodi- and tripeptides
• Convenient Syntheses of 3-Deoxy-D-manno-2-octulosonic Acid (KDO) and 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid (KDN) Derivatives from D-Mannose
• Convenient Synthesis of the Main Dehydrohexapeptide Skeleton Constituting a Macrocyclic Antibiotic, Berninamycin A
• Useful Synthesis of the Main Dehydrohexapeptide Segment of a Macrocyclic Antibiotic, Berninamycin B
• Total Syntheses of Bistratamides J, E, and H from Two Types of ΔAla-Containing Oligopeptides
• Novel Synthesis of the Main Central 2,3,6-Trisubstituted Pyridine Skeleton [Fragment A-B-C] of a Macrobicyclic Antibiotic, Cyclothiazomycin
• Convenient Synthesis of a Central 2,3,6-Trisubstituted Pyridine Skeleton of a Macrobicyclic Antibiotic, Cyclothiazomycin
• Useful Synthesis of Fragment A-C-D of a Thiostrepton-type Macrocyclic Antibiotic, Thiocilline I
• Total Synthesis of Bistratamide G, a Metabolite of the Philippines Ascidian Lissoclinum bistratum, from Dehydrotripeptides
• Convenient Synthesis of the Main Tridehydropentapeptide Skeleton for a Macrocyclic Antibiotic, Sulfomycin I
• Asymmetric Synthesis of the Main Pyridine Skeleton for a Macrobicyclic Antibiotic, Cyclothiazomycin
• Convenient Synthesis of (3S, 5S)-5-Hydroxy- and (3R, 5S)-5-Chloropiperazic Acids of a Peptide Antibiotic, Monamycin G^3
• Dehydrooligopeptides. XX. Unusual Peptide Bond Cleavage of Dehydrotripeptide Esters Containing α-Dehydroamino Acid Residue at P_2 by Using Papain
• Dehydrooligopeptides. XVIII. Enzymatic Hydrolysis and Coupling of Dehydrodipeptide Esters Containing α-Dehydroamino Acid Residue by Using Papain
• Convenient Synthesis of Dehydrooligopeptides Containing α-Dehydroamino Acid Residue Alone
• Facile Syntheses of (s, s)-2, 3-Diaminobutyric Acid and the Acid Containing N-Terminal Tripeptide of Antrimycins
• α,β-Unsaturated Carboxylic Acid Derivatives. IV. General Synthesis of Unsaturated Unsymmetric 3,6-Disubstituted-2,5-piperazinediones
• Dehydrooligopeptides. XIII. Selective Enzymatic Hydrolysis of N-Protected .ALPHA.-Dehydroglutamic Acid Diesters and Their Analogs Using Papain as Catalyst.
• Dehydrooligopeptides. X. Useful synthetic method for (E)- and (Z)-isomers of dehydroaspartic acids, and their .DELTA.1,2-dehydrodipeptides by the base-catalyzed .BETA.-elimination.
• The synthesis and reaction of spiro(oxolane-2,2'-piperazine)-3',6'-diones with N-bromosuccinimide in the presence or absence of water.
• Synthesis of (3Z, 6E)-1-N-Methylalbonoursin, a New Metabolite from Streptomyces albus
• Dehydrooligopeptides. VIII. Convenient syntheses of various dehydrotyrosine derivatives protected with useful N,O-protecting groups via N-carboxy dehydrotyrosine anhydrides.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XIII. The synthesis and configuration of alkyl 2-acylamino-2-alkenoates and their cyclized 2,5-piperazinedione derivatives.
• Dehydrooligopeptides. XI. Facile syntheses of various kinds of dehydrodi- and tripeptides, and dehydroenkephalins containing .DELTA.Tyr residue by using N-carboxydehydrotyrosine anhydride.
• Dehydrooligopeptides. IX. Syntheses and conversions of .ALPHA.-dehydroglutamine derivatives to N-carboxy-.ALPHA.-dehydroglutamine anhydride and .DELTA.1-dehydroglutaminyldipeptides.
• Dehydrooligopeptides. III. Synthesis of (Z,Z)- and (Z,E)-geometric isomers of dehydrodipeptides and their base-catalyzed transformation to the hydantoin derivatives.
• The confirmation of the configuration of ethyl 2-bromo-3-nitro-2-alkenoate by 13C NMR spectroscopy.
• Dehydrooligopeptides. VI Facile transformation of .ALPHA.-phosphoranylideneamino-.ALPHA.-alkenoates to .DELTA.2-dehydrodipeptide derivatives.
• Dehydrooligopeptides. VII Convenient synthesis of various dehydrodi- and tripeptide esters by using N-carboxy .ALPHA.-dehydroamino acid anhydride.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XVII. The facile synthesis of ethyl .ALPHA.-azido-.ALPHA.-alkenoates and reduction to ethyl .ALPHA.-amino-.ALPHA.-alkenoates.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XIV. The synthesis and reduction of Diels-Alder adducts from ethyl 3-nitro-2-alkenoates and cyclopentadiene.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XV. The reaction of ethyl 3-nitro-2-alkenoate with bromine azide or bromine, and transformations of the products.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XXI. A novel synthesis of .ALPHA.-dehydroamino acid derivatives by the Arbusov reaction of .ALPHA.-phosphoranylideneamino-2-alkenoates.
• Dehydrooligopeptides. II. The synthesis of dehydrodehydrodipeptides by direct coupling and base-catalyzed .BETA.-elimination.
• Convenient Synthesis of Dehydrooligopeptides by the Solid Phase Method Using N-Carboxy α-Dehydroamino Acid Anhydride
• A Novel Synthesis of Ethyl β-Diethoxyphosphinyl-α,β-unsaturated-carboxylates
• The formation of the main skelton of bicyclomycin by the cyclization of 6-hydroxy-3-(3-hydroxypropyl)-2,5-piperazinedione derivatives.
• The Synthesis and Reaction of α,β-Unsaturated α-Nitrocarboxylic Esters
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XIX. The convenient synthesis of .ALPHA.-alkoxy-, .ALPHA.-hydroxy-.ALPHA.-amino acid, and its cyclic dipeptide from .ALPHA.-dehydroamino acid.
• A convenient synthesis of 6-hydroxy-7,9-bis(p-methoxybenzyl)-5-methylene-2-oxa-7,9-diazabicyclo(4.2.2)decane-8,10-dione.
• Oxidative removal of N-(4-methoxybenzyl) group on 2,5-piperazinediones with cerium(IV) diammonium nitrate.
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XII. A convenient synthesis of oxazole-4-carboxylic and 3,3-dibromo-2,2-diamino acids.
• α,β-Unsaturated Carboxylic Acid Derivatives. VIII. The Synthesis and Reaction of Esters N-Acyl-N-bromo-α-dehydroamino Acid
• Branched-Chain Sugars. II. On the Configuration of Branched-Chain Sugars from Methyl 2-O-Benzoyl-4,6-O-benzylidene-α-D-ribo-hexopyranosid-3-ulose
• α,β-Unsaturated Carboxylic Acid Derivatives. IX. The Cyclization of α-(N-Acyl-hydroxyamino) Acid Esters with Ammonia or Hydroxylamine
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XVI. Synthesis and configuration of Diels-Alder adducts from ethyl 3-nitro-2-alkenoate and 1,3-butadiene.
• α,β-Unsaturated Carboxylic Acid Derivatives. VI. New Synthesis of N-Acyl-α-dehydroamino Acid Esters
• α,β-Unsaturated Carboxylic Acid Derivatives. X. The Synthesis and Reaction of α-Azido-diethoxyphosphinyl-α- and β-alkenes
• Studies on Nitro Carboxylic Acids. III. The Reaction of α-Nitroolefins with Triethyl or Diethyl Phosphite
• .ALPHA.,.BETA.-Unsaturated carboxylic acid derivatives. XI. Convenient synthesis of tert-butyl 2-alkoxy- and hydroxy-2-acetylamino-3-mono- or 3,3-dihaloalkanoates.
• The Independent Isolation of a Primary Enamine and the Tautomeric Imine
• Convenient synthesis of 3-aminocoumarin derivatives by the condensation of 1,4-diacetyl-or 3-substituent-2,5-piperazinediones with various salicylaldehyde derivatives.
• The Reaction of α-Oxo Acids with N-Phenyltriphenylphosphinimine

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